# Genetic Counseling for an Infertile Couple With Premature Chromatid Separation (PCS) Syndrome: A Case Report

**Authors:** Sagiri Taguchi, Terumi Hayashi, Noriko Watanabe, Yoshihiro Tada, Takashi Matsubara, Giannina Calongos, Kiko Yamamoto, Risa Fujishima, Sayaka Imoto, Miyako Funabiki, Yoshitaka Nakamura

PMC · DOI: 10.7759/cureus.56921 · 2024-03-25

## TL;DR

This case report describes the first successful genetic counseling for an infertile couple with PCS syndrome, leading to a healthy baby.

## Contribution

The paper presents the first documented case of genetic counseling for PCS syndrome in an infertile couple.

## Key findings

- The couple received genetic counseling and decided to continue infertility treatment.
- They successfully gave birth to a healthy baby via caesarean section in May 2018.

## Abstract

We report the first case of successful genetic counseling for an infertile couple with premature chromatid separation (PCS) syndrome. After our careful genetic counseling, the couple decided to continue infertility treatment. As a result, they gave birth to a baby (girl: 2,930 g) by caesarean section in May 2018. To our knowledge, there have not been any published reports regarding genetic counseling for an infertile couple with PCS after PubMed, EMBASE, and Web of Science searches until March 2024.

## Full-text entities

- **Diseases:** Premature Chromatid Separation (PCS) Syndrome (OMIM:176430), infertility (MESH:D007246)

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11043054/full.md

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Source: https://tomesphere.com/paper/PMC11043054