# Autogenous structural bone graft reconstruction of ≥ 10-mm-deep uncontained medial proximal tibial defects in primary total knee arthroplasty

**Authors:** Ahmed Abdel-Monem Dewidar, Mohamed Kamal Mesregah, Mustafa Mohamed Mesriga, Ahmed Mohamed El-Behiry

PMC · DOI: 10.1186/s10195-024-00762-6 · Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology · 2024-04-23

## TL;DR

This study shows that using a patient's own bone grafts can effectively treat large bone defects during knee replacement surgery.

## Contribution

The study demonstrates the effectiveness of autogenous structural bone grafts for deep uncontained tibial defects in primary TKA.

## Key findings

- Significant improvement in Knee Society Score and WOMAC score after surgery.
- Mean graft union time was 4.9 months with no major complications.
- Range of motion increased significantly post-surgery.

## Abstract

Management of uncontained medial proximal tibial defects during primary total knee arthroplasty (TKA) can be challenging, especially for defects ≥ 10 mm in depth. This study sought to assess the outcomes of autogenous structural bone grafts to address these defects.

In this prospective study, patients with uncontained medial proximal tibial defects ≥ 10 mm in depth undergoing TKA were managed by autogenous structural bone grafts fixed by screws and were followed up for at least 36 months. Patients were followed-up clinically with Knee Society Score (KSS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Additionally, radiological follow-up was done to assess bone graft union and implant stability.

The study included 48 patients with a mean age of 69.2 ± 4.5 years. The mean body mass index (BMI) was 31.4 ± 3.7 kg/m2. The mean defect depth was 17 ± 3.6 mm. With a mean follow-up period of 52.2 ± 12.3 months, the median KSS improved significantly from 30 preoperatively to 89, P < 0.001. The median WOMAC score reduced significantly from 85 preoperatively to 30.5, P < 0.001. The mean ROM increased significantly from 73 ± 12.4 preoperatively to 124 ± 8.4 degrees, P < 0.001. The mean graft union time was 4.9 ± 1 months. No significant complications were reported.

Autogenous bone graft reconstruction is a safe and effective method of addressing uncontained medial proximal tibial defects in primary TKA.

Level IV.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** Osteoarthritis (MESH:D010003), defects (MESH:D000013)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC11039605/full.md

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Source: https://tomesphere.com/paper/PMC11039605