# A systematic review and meta-analysis on abnormal posturing among brain injury patients

## TL;DR

This study reviews and analyzes risk factors and outcomes of abnormal posturing in brain injury patients, focusing on factors affecting survival.

## Contribution

A systematic review and meta-analysis of abnormal posturing in brain injury patients, identifying key prognostic factors.

## Key findings

- Decerebrate posturing is more common in males and associated with specific types of brain injuries.
- Extradural and subdural hematomas with cerebral contusion are frequently linked to surgical interventions.
- Lesion type, age, and operative procedures significantly influence survival outcomes.

## Abstract

Background
 Abnormal motor posturing (AMP), exhibiting as decorticate, decerebrate, or opisthotonos, is regularly noticed among children and adults.

Objective
 This systematic review and meta-analysis examined the risk factors and outcome of posturing among severe head and brain injury subjects.

Methods
 Based on the inclusion and exclusion criteria and using MeSH terms: “decerebrate posturing”, “opisthotonic posturing”, “brain injury”, and/or “cerebral injury” articles were searched on Scopus, PubMed, Science Direct, and google scholar databases. Observational studies, case series, and case reports were included.

Results
 A total of 1953 studies were retrieved initially, and based on the selection criteria, 20 studies were finally selected for review and were analyzed for meta-analysis based on the mortality between the hematomas. The functional outcomes of this study are the risk factors, mortality rate and Glasgow Outcome Scale. Decerebrative patients were higher among the studies related to head injury surgeries. Males were mainly treated for decerebrate postures compared with the female subjects. Extradural hematoma and acute subdural hematoma with cerebral contusion were quite common in the surgical mass lesions.

Conclusion
 The findings reported that the lesion types, the operative procedures, and the age of the decerebrating patients with brain injuries are the significant prognostic factors determining the survival outcomes.