# D-Transposition of Great Arteries With Infective Endocarditis and Congestive Cardiac Failure: A Case Report

**Authors:** Chandrakant M Bokade, Nisha R Aglave, Pooja B Nagrale

PMC · DOI: 10.7759/cureus.56832 · Cureus · 2024-03-24

## TL;DR

A rare case of d-TGA with infective endocarditis and heart failure in a child is reported, highlighting unusual complications.

## Contribution

This case report presents an unusual combination of d-TGA, infective endocarditis, and congestive cardiac failure in a pediatric patient.

## Key findings

- A five-and-a-half-year-old child presented with cyanosis, CCF, and infective endocarditis.
- The case involved d-TGA with pulmonary stenosis and a ventricular septal defect.
- Infective endocarditis with mitral valve regurgitation is a rare complication in d-TGA patients.

## Abstract

Embryological misalignment between the aorta and pulmonary trunk gives rise to the congenital anomaly of the heart known as transposition of the great arteries (TGA). TGA is a type of parallel circulation, where the heart pumps oxygenated blood from the left ventricle into the pulmonary trunk. The deoxygenated blood from the right ventricle is circulated into the body as it pumps blood into the aorta. This type of parallel circulation is not compatible with life unless there is communication between oxygenated and deoxygenated blood. The presence of a ventricular septal defect (VSD) or patent ductus arteriosus (PDA) in TGA patients serves as this communication. Cyanosis in the first month of life is the most common presenting feature. We had a five-and-a-half-year-old male child presenting with cyanosis and congestive cardiac failure (CCF), along with infective endocarditis with mitral valve regurgitation, which is an unusual complication of dextro-TGA (d-TGA) with pulmonary stenosis (PS) with VSD.

## Linked entities

- **Diseases:** transposition of the great arteries (MONDO:0000153), infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** Infective Endocarditis (MESH:D004696), congenital anomaly of the heart (OMIM:600001), Cyanosis (MESH:D003490), CCF (MESH:D006333), TGA (MESH:D014188), PS (MESH:D011666), VSD (MESH:D006345), PDA (MESH:D004374), mitral valve regurgitation (MESH:D008944)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11036022/full.md

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Source: https://tomesphere.com/paper/PMC11036022