# Progress of research on the relationship between efferocytosis and tumor

**Authors:** Xuexin Yao, Ling Zhang, Siyi Sun, Aishuang Fu, Yanlei Ge

PMC · DOI: 10.3389/fonc.2024.1361327 · Frontiers in Oncology · 2024-04-09

## TL;DR

This paper explores how efferocytosis, a process involving macrophages, influences tumor development and progression.

## Contribution

The paper highlights the emerging role of efferocytosis in tumor-associated macrophages and calls for further investigation into its mechanisms.

## Key findings

- Tumor-associated macrophages play a critical role in tumor progression through efferocytosis.
- More research is needed to understand how efferocytosis contributes to tumor pathology.
- New therapeutic strategies targeting efferocytosis could be developed.

## Abstract

Tumors are genetic changes that develop in an organism as a result of many internal and external causes. They affect the biological behavior of cells, cause them to grow independently, and give rise to new, perpetually proliferating organisms. Recent research has supported the critical function of tumor-associated macrophages in the development, progression, and metastasis of tumors through efferocytosis. Yet, there is still much to learn about the mechanisms behind their contribution to tumor pathological processes. As a result, it’s critical to actively investigate how cytosolic processes contribute to the growth of tumors and to create novel therapeutic approaches.

## Full-text entities

- **Diseases:** Tumors (MESH:D009369), metastasis of (MESH:D009362)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11035832/full.md

## References

82 references — full list in the complete paper: https://tomesphere.com/paper/PMC11035832/full.md

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Source: https://tomesphere.com/paper/PMC11035832