# A case report of typical well-differentiated papillary mesothelial tumor diagnosed by internal thoracoscopy and literature review

**Authors:** Jian Guo, XiaoHui Lv, Wei Zhang, Fang Dong, Lei Li, Juan Liu, Bing Li

PMC · DOI: 10.3389/fonc.2024.1359985 · Frontiers in Oncology · 2024-04-09

## TL;DR

A rare benign pleural tumor was diagnosed in a patient with long-term pleural effusions using internal thoracoscopy, highlighting its usefulness for difficult cases.

## Contribution

Demonstrates the effectiveness of internal thoracoscopy in diagnosing minimal pleural lesions not visible on CT scans.

## Key findings

- Internal thoracoscopy successfully diagnosed a well-differentiated papillary mesothelial tumor in a patient with recurrent pleural effusions.
- The tumor was benign and preinvasive, with a long clinical history of over 35 years.
- CT scans failed to detect the minimal lesion, emphasizing the need for alternative diagnostic methods.

## Abstract

We report a case of well-differentiated papillary mesothelial tumor (WDPMT) diagnosed using internal thoracoscopic biopsy in a patient who has suffered from recurrent pleural effusions for over 35 years together with a history of elevated CA125. We hope to provide a case for the diagnosis of this rare benign and preinvasive pleural tumor and recommend that internal thoracoscopy may be a good choice in these recurrent pleural effusion patients especially for those minimal lesions not easily detected using CT scan.

## Linked entities

- **Proteins:** MUC16 (mucin 16, cell surface associated)

## Full-text entities

- **Genes:** MUC16 (mucin 16, cell surface associated) [NCBI Gene 94025] {aka CA125}
- **Diseases:** pleural effusion (MESH:D010996), pleural tumor (MESH:D010997), WDPMT (MESH:D018301)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11035803/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11035803/full.md

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Source: https://tomesphere.com/paper/PMC11035803