# Examining the Efficacy of 38% Silver Diamine Fluoride in Halting Active Dental Caries Lesions Among Children: A Descriptive Study

**Authors:** Ayesha Saleem, Afshan Manzoor, Amara Nazir, Humara Iqbal, Muhammad A Khan, Zohaib Ahmed, Mustafa Sajid, Muhammad Kashif

PMC · DOI: 10.7759/cureus.56762 · 2024-03-23

## TL;DR

This study shows that 38% silver diamine fluoride is very effective at stopping tooth decay in children.

## Contribution

The study provides new evidence on the high efficacy of 38% silver diamine fluoride in arresting dental caries in children.

## Key findings

- 38% silver diamine fluoride halted active dental caries lesions in 95.62% of children.
- The treatment was effective across a wide age range of children (3-9 years).

## Abstract

Background/objectives: Dental caries, a prevalent issue among children, often leads to discomfort and potential complications. Utilizing caries-arresting treatments to slow down its progression offers a practical alternative. Previous research indicates that topical fluorides can deactivate and remineralize enamel caries. This study aims to evaluate the efficacy of 38% silver diamine fluoride (SDF) in halting active dental caries lesions in children.

Materials and methods: This descriptive case series was conducted at the Operative Dentistry Department of the Nishtar Institute of Dentistry in Multan, Pakistan. We enrolled 753 patients aged three to nine years, of both genders, each with at least one cavitated lesion graded 3-6 according to the International Caries Detection and Assessment System (ICDAS). SDF was directly applied to dried and isolated teeth using a micro brush and left to absorb for up to two minutes (adjusted based on the child's cooperation), and parents were instructed to ensure the child refrained from eating or drinking for an hour post-application. Baseline examinations were performed by consultant restorative dentists, and reexaminations were conducted after two to three weeks by a consultant unaware of the study.

Results: The study included children aged three to nine years, with a mean age of 6.02±1.35 years. The majority of patients (61.75%) were aged between three and six years. Among the 753 patients, 619 (82.20%) were male, and 134 (17.80%) were female, with a male-to-female ratio of 4.6:1. The efficacy of 38% SDF in arresting active dental caries lesions in children was observed in 720 (95.62%) patients.

Conclusion: This study demonstrates that 38% SDF is highly effective in halting active dental caries lesions in children.

## Linked entities

- **Chemicals:** silver diamine fluoride (PubChem CID 161820)
- **Diseases:** dental caries (MONDO:0005276)

## Full-text entities

- **Diseases:** Caries (MESH:D003731), cavitated lesion (MESH:D009059)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11033969/full.md

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Source: https://tomesphere.com/paper/PMC11033969