# Clinical Overlaps in Reticulate Pigmentary Disorders: A Study of Three Cases

## TL;DR

This paper presents three cases of skin disorders with similar symptoms caused by genetic issues in keratin genes, which are hard to treat.

## Contribution

The study highlights clinical overlaps among three rare pigmentary disorders with limited treatment options.

## Key findings

- Three cases showed overlapping features of reticulate acropigmentation of Kitamura, Dowling-Degos disease, and dyschromatosis symmetrica hereditaria.
- All disorders are linked to abnormalities in keratin 5 and keratin 14 genes.
- Treatment options for these conditions remain limited.

## Abstract

Reticulate pigmentary disorders are autosomal dominant pigmentary disorders caused by abnormalities in the keratin 5 and keratin 14 genes. Here, we report three cases of reticulate hyperpigmentation disorders with clinical overlaps of the reticulate acropigmentation of Kitamura, Dowling-Degos disease (DDD), and dyschromatosis symmetrica hereditaria (DSH), all three having limited treatment options.