Sex as a risk factor regarding presbyopia in the rhesus monkey

TL;DR

This study found that presbyopia, or age-related loss of focusing ability, occurs similarly in male and female rhesus monkeys.

Contribution

The study demonstrates that sex does not significantly influence the progression of presbyopia in rhesus monkeys.

Findings

Accommodative amplitude decreased with age in both male and female rhesus monkeys.

There was no significant difference in the rate of accommodative decline between sexes (p = 0.827).

Presbyopia progression is consistent and predictable, regardless of sex.

Abstract

To determine the effect of sex as a risk factor regarding presbyopia.

Maximum accommodation was pharmacologically induced (40% cabachol corneal iontophoresis) in 97 rhesus monkeys (49 males and 48 females) ranging in age from 8 to 36 years old. Accommodation was measured by Hartinger coincidence refractometry.

Accommodative amplitude measured refractometrically decreased with age, and the rate of change was not different between males and females (p = 0.827).

Presbyopia is essentially sex neutral, and no one is spared. There may be modest variations between different populations for various reasons, but essentially it is monotonously predictable. At present there is no biological therapeutic.

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