700 Early Heart Rate Trend Predicts Burn Mortality
Arushi Biswas, Keith T Kuo, Shanmuga Priya Rajagopalan, Terrence Tsou, Tomer Lagziel, Madhu Subramanian, Carisa M M Cooney, Julie A Caffrey

TL;DR
This study shows that a small increase in heart rate in the first 48 hours after a severe burn is linked to higher mortality risk, helping clinicians identify high-risk patients early.
Contribution
The study introduces heart rate trend in the first 48 hours as a novel, accessible predictor of mortality in burn patients.
Findings
Patients who died had a 9% heart rate increase in 48 hours, compared to 20% in survivors.
Heart rate trend was a significant predictor of 90-day mortality after adjusting for key confounders.
Early heart rate trends can guide resource allocation and clinical focus in burn care.
Abstract
During post-burn hypermetabolism, tachycardia is considered a compensatory response to sustain cardiac output and oxygenation to essential organs. Although heart rate variability predicts mortality in burn patients, many centers lack access to non-invasive measurement methods. We hypothesized that heart rate trend in the first 48 hours of admission (measured via vital signs monitor) could predict mortality in burn patients. We performed a retrospective review of 128 patients treated for burns with TBSA ≥ 20% at a single institution between 2016 and 2021. We extracted demographics, burn characteristics (e.g. location, mechanism, depth, presence of inhalation injury), complications (surgical and hospital-acquired), and hourly vital signs for the first 48 hours of admission. We performed bivariate analyses to determine associations between mortality within 90 days of discharge and patient…
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Taxonomy
TopicsHealthcare Systems and Public Health
