# Desmosomes in heart and skin: friends or foes?

**Authors:** Giuseppina Caiazzo, Rosa Redenta De Simone, Emanuele Monda, Ferdinando Barretta, Fabiana Uomo, Cristina Mazzaccara, Matteo Megna, Limongelli Giuseppe, Giulia Frisso

PMC · DOI: 10.1186/s12967-024-05137-3 · Journal of Translational Medicine · 2024-04-16

## Full-text entities

- **Genes:** DES (desmin) [NCBI Gene 1674] {aka CDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R}, DSP (desmoplakin) [NCBI Gene 1832] {aka DCWHKTA, DP}, JUP (junction plakoglobin) [NCBI Gene 3728] {aka CTNNG, DP3, DPIII, PDGB, PG, PKGB}, PKP2 (plakophilin 2) [NCBI Gene 5318] {aka ARVD9}, DSG2 (desmoglein 2) [NCBI Gene 1829] {aka CDHF5, HDGC}, DSC2 (desmocollin 2) [NCBI Gene 1824] {aka ARVD11, CDHF2, DG2, DGII/III, DSC3}
- **Diseases:** plantar hyperkeratosis (MESH:D016523), basal cell carcinoma (MESH:D002280), ACM (MESH:D019571), SCD (MESH:D016757), nevi (MESH:D009506), and hair (MESH:D006201), dermatological disorder (MESH:D000168), acne (MESH:D000152), LB (MESH:C537419), rosacea (MESH:D012393), hereditary cardiomyopathies (MESH:D009386), ventricular arrhythmias (MESH:D001145), condyloma (MESH:D062688), dilated cardiomyopathy (MESH:D002311), dyshidrotic eczema (MESH:D011146), cardiomyopathies (MESH:D009202), heart-muscle disease (MESH:D006331), fungal infections (MESH:D009181)
- **Chemicals:** Caiazzo (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** c.2134G > A, C > T, c.1996G > C, rs764817683, c.764T > A, c.368G > A, A > G, rs727504542

## Full text

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11022482/full.md

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Source: https://tomesphere.com/paper/PMC11022482