Sarcoidosis Resembling Angiokeratomas: A Case Report

TL;DR

A 74-year-old woman with sarcoidosis presented with unusual skin lesions resembling angiokeratomas, highlighting the need for clinicians to recognize atypical skin signs of the disease.

Contribution

This case report documents a previously unreported cutaneous manifestation of sarcoidosis that can mimic other conditions.

Findings

The patient's skin lesions showed nodular and angiocentric granulomatous inflammation consistent with sarcoidosis.

Chest radiography revealed bilateral hilar opacities, supporting the sarcoidosis diagnosis.

The case emphasizes the importance of considering sarcoidosis in atypical skin presentations.

Abstract

Sarcoidosis, a multifaceted systemic disorder characterized histologically by the presence of non-caseating granulomas, has a wide array of cutaneous manifestations. We describe a case of a 74-year-old woman with a complex medical history, who presented with asymptomatic hyperpigmented papules on her lower extremities. Histological examination of a punch biopsy specimen showed nodular and angiocentric patterns of granulomatous inflammation consistent with sarcoidosis, and chest radiography demonstrated bilateral hilar opacities, supporting the diagnosis. To our knowledge, this specific cutaneous presentation of sarcoidosis has not been described before, and it can easily be mistaken for other conditions. Therefore, this case underscores the importance of recognizing atypical cutaneous morphologies of sarcoidosis, particularly in patients with complex medical histories, to facilitate accurate diagnosis and timely intervention. We aim to increase awareness among clinicians regarding the diverse manifestations of sarcoidosis, thereby enhancing diagnostic acumen and patient care.

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