Featured Cover
Mariann M. Gabrawy, Reyhan Westbrook, Austin King, Nick Khosravian, Neeraj Ochaney, Tagide DeCarvalho, Qinchuan Wang, Yuqiong Yu, Qiao Huang, Adam Said, Michael Abadir, Cissy Zhang, Pratik Khare, Jennifer E. Fairman, Anne Le, Ginger L. Milne, Fernando J. Vonhoff
TL;DR
This study shows that combining two types of treatments can significantly extend the lifespan of fruit flies.
Contribution
The novel finding is that dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila.
Findings
Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila.
The combination of these treatments produces a greater lifespan extension than either treatment alone.
Abstract
Cover legend: The cover image is based on the Research Article Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila by Mariann M. Gabrawy et al., https://doi.org/10.1111/acel.14102 Image Credit: Jennifer E. Fairman, CMI, FAMI, © JHUAAM.
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Taxonomy
TopicsTryptophan and brain disorders · Calcium signaling and nucleotide metabolism · Sirtuins and Resveratrol in Medicine