# Trypan Blue and Endoillumination-Assisted Phacoemulsification in a Patient With Advanced Keratoglobus

**Authors:** Yumna F Kamal, Mazen Alzahrani, Halah Bin Helayel, Sami T Hameed

PMC · DOI: 10.7759/cureus.56265 · Cureus · 2024-03-16

## TL;DR

A modified phacoemulsification technique using trypan blue and endoillumination was successfully used in a patient with advanced keratoglobus to improve surgical visualization and reduce complications.

## Contribution

A modified surgical technique for cataract removal in patients with severe corneal opacity due to keratoglobus is presented.

## Key findings

- The technique improved visualization during surgery in a patient with severe corneal opacity.
- The patient had no postoperative leaks and recovered well.
- The method may reduce intraoperative complications in similar cases.

## Abstract

Keratoglobus is a rare subset of noninflammatory corneal ectasia, which is a group of disorders characterized by corneal thinning, projection, and scarring. Patients with keratoglobus commonly present with poor vision. A case of advanced keratoglobus was managed by a modified phacoemulsification surgical technique using endoillumination and capsular staining with trypan blue. In this case, we present a 54-year-old man with keratoglobus. In January 2023, a modified phacoemulsification surgical technique using endoillumination was described with a video in a patient with bilateral corneal opacification, neovascularization, significant peripheral thinning, and moderate to severe corneal opacity in which cataract surgery had to be performed alone without considering penetrating keratoplasty. Postoperatively, the patient was doing well with no leaks. We may conclude that this method allows for better visualization during surgery and decreases the risk of intraoperative complications due to poor visualization in patients with severe corneal opacity.

## Linked entities

- **Chemicals:** trypan blue (PubChem CID 6296)

## Full-text entities

- **Diseases:** corneal opacification (MESH:C537775), cataract (MESH:D002386), neovascularization (MESH:D016510), corneal ectasia (MESH:D004108), corneal thinning (MESH:D013851), Keratoglobus (MESH:D007640), leaks (MESH:D019559), corneal opacity (MESH:D003318)
- **Chemicals:** Trypan Blue (MESH:D014343)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11017366/full.md

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Source: https://tomesphere.com/paper/PMC11017366