# Uncommon using of the pulmonary homograft in oncological case - three years follow up

**Authors:** Dhaker Lahidheb, Roman Komarov, Ruslan Alikhanov, Boris Tlisov, Alisher Ismailbaev, Ines Dhif

PMC · DOI: 10.1186/s13019-024-02684-0 · Journal of Cardiothoracic Surgery · 2024-04-13

## TL;DR

This paper presents a unique surgical case using a cryopreserved pulmonary homograft to treat advanced colorectal cancer with rare metastasis to the heart and vena cava.

## Contribution

The first reported use of a cryopreserved pulmonary homograft for radical resection in a complex oncological case involving heart and vena cava metastasis.

## Key findings

- A cryopreserved pulmonary homograft was successfully used for radical resection in a case of colorectal cancer with metastasis to the inferior vena cava and right atrium.
- The homograft allowed replacement of an extended section of the inferior vena cava during surgery involving cardiopulmonary bypass.
- The approach potentially reduced the risk of postoperative thrombosis in both short- and long-term recovery.

## Abstract

There are enough cases of colorectal cancer with liver metastasis, but inferior vena cava infiltraion with dissemination to the right atrium is an infrequent event.

This is the first case of surgical treatment of recurrent liver metastasis with the infiltration to the inferior vena cava and to the right atrium of the heart, using a cryopreserved pulmonary homograft.

The choice of a cryopreserved pulmonary homograft was preferred by the need for a radical and wide resection of tissues involved in the metastasis, as well as to potentially reduce the risk of thrombosis in the short- and long-term postoperative period.

The use of a cryopreserved homograft in operation undergoing cardiopulmonary bypass allowed us to perform the required volume of radical resection and to replace an extended section of the inferior vena cava.

## Linked entities

- **Diseases:** colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** colorectal cancer (MESH:D015179), cava (MESH:D013479), liver metastasis (MESH:D009362), thrombosis (MESH:D013927)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11015555/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11015555/full.md

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Source: https://tomesphere.com/paper/PMC11015555