# Revised whole genome and DNA methylome of Mycobacterium marinum type strain ATCC 927T

**Authors:** Kirsi Savijoki, Paulina Deptula, Richard J. Roberts, Milka Hammarén, Jari Yli-Kauhaluoma, Pekka Varmanen, Mataleena Parikka

PMC · DOI: 10.1128/mra.01016-23 · Microbiology Resource Announcements · 2024-02-28

## TL;DR

Researchers updated the genome and DNA methylation data of Mycobacterium marinum to better study its role in disease and tuberculosis mechanisms.

## Contribution

A new reference genome and DNA methylome for M. marinum ATCC 927T are provided to enhance research on pathogenesis.

## Key findings

- A revised whole genome sequence for M. marinum ATCC 927T was generated.
- The DNA methylome of the same strain was characterized.
- The updated data aims to improve understanding of tuberculosis-like disease mechanisms.

## Abstract

Mycobacterium marinum, a slow-growing Actinobacterium, typically induces tuberculosis-like disease in fish. Here, we report a new reference sequence for M. marinum ATCC 927T, along with its DNA methylome. This aims to maximize the research potential of this type strain and facilitates investigations into the pathomechanisms of human tuberculosis.

## Linked entities

- **Species:** Mycobacterium marinum (taxon 1781)

## Full-text entities

- **Diseases:** tuberculosis (MESH:D014376)
- **Species:** Actinomycetes bacterium (species) [taxon 1883427], Homo sapiens (human, species) [taxon 9606], Mycobacterium marinum (species) [taxon 1781]

## Full text

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## Figures

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## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC11008211/full.md

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Source: https://tomesphere.com/paper/PMC11008211