# A rare presentation of spontaneous splenic rupture from plasma cell leukaemia—a case report

**Authors:** Hershil Khatri, Nakhyun Kim, Tzu-Yi (Arron) Chuang, Michael Lamparelli

PMC · DOI: 10.1093/jscr/rjae223 · Journal of Surgical Case Reports · 2024-04-11

## TL;DR

An 82-year-old man with plasma cell leukemia experienced a rare spontaneous splenic rupture and recovered after treatment.

## Contribution

This case highlights plasma cell leukemia as a rare cause of spontaneous splenic rupture.

## Key findings

- Spontaneous splenic rupture was diagnosed in a patient with plasma cell leukemia.
- The patient recovered after splenectomy and chemotherapy.
- Plasma cell leukemia can present with splenic complications due to thrombocytopenia.

## Abstract

Spontaneous/atraumatic splenic rupture is rare, and often associated with underlying infectious disease, or haematological malignancy. Plasma cell leukaemia (PCL) is a rare and aggressive subtype of multiple myeloma, with a higher prevalence of hepatosplenomegaly with a bleeding diathesis from secondary to thrombocytopaenia. We report the case of an 82-year-old male presenting to the emergency department with altered mentation and complaints of left abdominal pain. He presented with haemorrhagic shock. Imaging revealed a spontaneous splenic rupture. He underwent emergency laparotomy and splenectomy for which the histopathology yielded a diagnosis of PCL as the cause for rupture. He received four courses of bortezomib and hyperCVAD 1A therapy. After a long 64-day admission, he recovered well and was discharged home with outpatient haematology/oncology follow-up.

## Linked entities

- **Chemicals:** bortezomib (PubChem CID 387447)
- **Diseases:** multiple myeloma (MONDO:0009693)

## Full-text entities

- **Diseases:** bleeding diathesis (MESH:D006474), haematological malignancy (MESH:D009369), infectious disease (MESH:D003141), PCL (MESH:D007952), haemorrhagic shock (MESH:D012771), multiple myeloma (MESH:D009101), hepatosplenomegaly (MESH:C535727), rupture (MESH:D012421), abdominal pain (MESH:D015746), splenic rupture (MESH:D013161)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11007546/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11007546/full.md

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Source: https://tomesphere.com/paper/PMC11007546