# Alcohol Dependence Syndrome With Bipolar Affective Disorder and Hypomanic Current Episode: A Case Report

**Authors:** Sharayu P Wankhade, Joel Gibbs

PMC · DOI: 10.7759/cureus.55994 · Cureus · 2024-03-11

## TL;DR

This case report explores a patient with alcohol dependence and bipolar disorder, highlighting the complex relationship between these conditions and the need for further research on effective treatments.

## Contribution

The paper presents a clinical case emphasizing the co-occurrence of alcohol dependence and bipolar disorder, suggesting a need for more targeted treatment strategies.

## Key findings

- The patient exhibited symptoms of alcohol dependence and hypomanic episodes consistent with bipolar disorder.
- Current treatments for co-occurring alcoholism and bipolar disorder remain limited and require further investigation.
- Psychosocial interventions and medications like valproate and lithium have been explored but lack conclusive evidence for efficacy.

## Abstract

Studies have revealed that individuals with bipolar I and bipolar II have a past of substance abuse. The co-occurrence of bipolar disorder and alcoholism is frequent. Although various arguments have been put forward to explain the relationship between these disorders, it is still not fully understood. Since substance abuse is prevalent among bipolar patients, it would be beneficial to investigate the impact of substance abuse on clinical characteristics, as well as the progression of the illness. Thus, this study was carried out to investigate a case of alcohol dependence with bipolar disorder. A 49-year-old male visited the psychiatry outpatient department and then was admitted. The patient's chief complaints were alcohol consumption, cigarette smoking, daily drinking for 35 years, irritability/aggressiveness, boastful talk, overspending, and decreased need for sleep from the last 20 days. According to the literature, self-medicating with alcohol is not an effective treatment for alcoholism, unless it is being used to alleviate the psychological and neurochemical effects caused by alcohol. However, there has been limited research on how to treat individuals who have both alcoholism and another medical condition. A few studies have looked at the impact of medications like valproate, lithium, and naltrexone, as well as psychosocial interventions, in treating patients with bipolar disorder and alcoholism. However, more research is necessary to fully understand the best approach.

## Linked entities

- **Diseases:** alcohol dependence (MONDO:0002046), bipolar disorder (MONDO:0004985)

## Full-text entities

- **Diseases:** aggressiveness (MESH:D010554), Alcohol Dependence Syndrome (MESH:D000437), Bipolar Affective Disorder (MESH:C564108), substance abuse (MESH:D019966), Hypomanic (MESH:D001714), irritability (MESH:D001523)
- **Chemicals:** valproate (MESH:D014635), lithium (MESH:D008094), naltrexone (MESH:D009271), alcohol (MESH:D000438)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC11007288/full.md

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Source: https://tomesphere.com/paper/PMC11007288