Correction: An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing
Raymond W. Wong, Ahalya Balachandran, Peter K. Cheung, Ran Cheng, Qun Pan, Peter Stoilov, P. Richard Harrigan, Benjamin J. Blencowe, Donald R. Branch, Alan Cochrane

Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Figure 1
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Taxonomy
TopicsRNA Research and Splicing · RNA modifications and cancer · interferon and immune responses
There is an error in the underlying blot data in part H of S2 Fig, which supports the western blot panels in part A of S11 Fig. The anti-P-p38 and Anti-p38 panels of the originally published S2H Fig are from a replicate experiment. With this notice the authors provide a corrected S2H Fig including the full-length blots that correspond to the anti-P-p38 and anti-p38 panels in Fig S11A.
The authors provide the following additional clarifications:
In the caption of Fig 1 of [1], it is stated that the lanes in Figs D-E were cropped/assembled from the same blots and the underlying blot images are available as Figs S2A and S2B of the original article [1]; however, the reassembly of these lanes was not clearly marked on the figure. To ensure best practice, the authors provide an updated version of Fig 1 indicating where lanes within the blots provided in the Supporting Information have been reassembled.
Some control blot and microscopy data were previously published in [2] and [3], but the intentional reuse of these data and attribution to these earlier publications were not reported in [1]. Specifically, DMSO-treated cells in this study were tested simultaneously with a number of other RNA processing inhibitors reported in [2] and [3]. The same representative blot and microscopy images were used in [1] as follows:
The authors apologize for the error in the published article.
Supporting information
S2 FigGel/blots used for representative figures.Lanes from continuous and unexcised gel/blots were cropped and rearranged for Fig 1D (A) and 1E (B), Fig 2I and 2J (C-D), S5 Fig (E), S6 Fig (F), S7A Fig (G), S11A Fig (H), S11B (I), S11C Fig (J), S11D Fig (K-L), and S13C Fig (M). The experimental conditions used in each gel/blot(s) can be found under the representative Fig(s) or Supporting Fig(s) listed and associated with it.(TIF)
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Wong RW, Balachandran A, Cheung PK, Cheng R, Pan Q, Stoilov P, et al. (2020) An activator of G protein-coupled receptor and MEK 1/2-ERK 1/2 signaling inhibits HIV-1 replication by altering viral RNA processing. P Lo S Pathog 16(2): e 1008307. 10.1371/journal.ppat.1008307 32069328 PMC 7048317 · doi ↗ · pubmed ↗
- 2Wong RW, Balachandran A, Ostrowski MA, Cochrane A (2013) Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing. P Lo S Pathog 9(3): e 1003241. 10.1371/journal.ppat.1003241 23555254 PMC 3610647 · doi ↗ · pubmed ↗
- 3Balachandran A., Wong R., Stoilov P. et al. Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation. Retrovirology 14, 7 (2017). 10.1186/s 12977-017-0330-0 28122580 PMC 5267425 · doi ↗ · pubmed ↗
