# Harnessing Neuroplasticity: A Case Report on Physiotherapy Rehabilitation for Millard-Gubler Syndrome

**Authors:** Anushri R Patil, Snehal Samal, Anam R Sasun

PMC · DOI: 10.7759/cureus.55894 · Cureus · 2024-03-10

## TL;DR

This case report shows how physiotherapy helped a woman recover from a rare brainstem stroke called Millard-Gubler syndrome.

## Contribution

The paper highlights the effectiveness of physiotherapy interventions in motor recovery for a rare pontine infarction syndrome.

## Key findings

- Physiotherapy improved gaze stability, hypertonia, and mobility in a patient with Millard-Gubler syndrome.
- Standardized measures showed measurable motor recovery and functional improvement over time.
- Multidisciplinary physiotherapy approaches can enhance outcomes in rare neurological conditions.

## Abstract

This case report glances at the physiotherapy management and motor recovery outcomes of a 47-year-old female who had a pontine infarction complicated by Millard-Gubler syndrome. Pontine infarction is a stroke that occurs in the pons region of the brainstem, resulting in impaired blood flow and subsequent tissue damage. Millard-Gubler syndrome, a rare form of pontine infarction, is distinguished by ipsilateral abducens (sixth cranial nerve) and facial (seventh cranial nerve) nerve palsy, which cause horizontal gaze palsy and facial weakness, respectively. Other common symptoms include contralateral hemiparesis or hemiplegia, dysarthria, and hypertonia. In this case, the patient had nystagmus, dysarthria, hypertonia, decreased consciousness, and limited mobility. Physiotherapy interventions were used in a multidisciplinary approach to address these deficits, with a focus on improving gaze stability, reducing hypertonia, facilitating bed mobility, and improving respiratory function. The outcomes were evaluated using standardised measures such as the Brunnstrom staging for motor recovery, the Modified Ashworth Scale for hypertonia, and the Functional Independence Measure for functional status. This case demonstrates the critical role of physiotherapy in improving motor recovery and functional outcomes.

## Full-text entities

- **Diseases:** hemiplegia (MESH:D006429), hypertonia (MESH:D009122), dysarthria (MESH:D004401), Millard-Gubler Syndrome (MESH:D020526), horizontal gaze palsy (MESH:C564593), blood flow (MESH:D054318), abducens (sixth cranial nerve) and facial (seventh cranial nerve) nerve palsy (MESH:D003389), Pontine infarction (MESH:D007238), stroke (MESH:D020521), contralateral hemiparesis (MESH:D010291), decreased consciousness (MESH:D003244), nystagmus (MESH:D009759), facial weakness (MESH:D018908)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11002708/full.md

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Source: https://tomesphere.com/paper/PMC11002708