# It is not “just a fracture”

**Authors:** Peggy M Cawthon, Matthew Drake

PMC · DOI: 10.1093/jbmrpl/ziae022 · 2024-04-09

## TL;DR

Hip and vertebral fractures are linked to high mortality rates, especially in men and the elderly, suggesting a critical need for immediate interventions to improve survival.

## Contribution

The study highlights the critical post-fracture period and emphasizes the need for urgent interventions to improve survival outcomes.

## Key findings

- Survival rates after hip or vertebral fractures are significantly lower compared to prostate and breast cancers.
- Mortality risk peaks within one month of fracture occurrence.
- Men and the oldest old experience the worst survival outcomes following fractures.

## Abstract

In their recent population–based study of nearly 100 000 patients from Ontario, Canada, who had suffered a fracture, Vincent et al. characterized postfracture survival rates. Their findings showed that overall survival was decreased particularly following fractures of the hip or vertebrae, and was worse in men and the oldest old. They found that relative survival, particularly after hip fracture, is strikingly poor with less than one-third of men and one-half of women surviving for 5 years following hip fracture, survival which was far less than that seen for patients afflicted by both prostate and breast cancers. Importantly, mortality risk increased immediately after fracture occurrence and was highest within 1 month of fracture. Collectively, their data suggest that a short, critical window may exist immediately following fracture in which application of interventions to improve survival is likely to be of greatest value. Future work is urgently needed to identify the best approaches to employ during this critical time period in order to optimize survival in patients who have suffered a fracture.

## Linked entities

- **Diseases:** hip fracture (MONDO:0005327), prostate cancer (MONDO:0005159), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** fractures of the hip or vertebrae (MESH:D006620), prostate and breast cancers (MESH:D001943), fracture (MESH:D050723)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC11001754