The roles of pyroptosis in genitourinary diseases

TL;DR

This review explores how pyroptosis, a type of cell death, contributes to urinary diseases and suggests it could be a new target for treatment.

Contribution

The paper provides a comprehensive review of pyroptosis's role in genitourinary diseases, highlighting its potential as a therapeutic target.

Findings

Pyroptosis is linked to the development of both benign and malignant urinary diseases.

The review identifies pyroptosis as a potential therapeutic target for treating urinary conditions.

Current research suggests pyroptosis plays a key role in disease progression.

Abstract

Pyroptosis, a form of programmed cell death distinct from apoptosis and necrosis, is thought to be closely associated with the pathogenesis of diseases. Recently, the association between pyroptosis and urinary diseases has attracted considerable attention, and a comprehensive review focusing on this issue is not available. In this study, we reviewed the role of pyroptosis in the development and progression of benign urinary diseases and urinary malignancies. Based on this, pyroptosis has been implicated in the development of urinary diseases. In summary, this review sheds light on future research directions and provides novel ideas for using pyroptosis as a powerful tool to fight urinary diseases.

Figures