# Safety evaluation of the food enzyme preparation D‐psicose 3‐epimerase from the non‐genetically modified Microbacterium foliorum strain SYG27B

**Authors:** Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Magdalena Andryszkiewicz, Laura Sanmartin Cabo, Ana Criado, Cristina Fernàndez‐Fraguas, Yi Liu, Silvia Peluso, Rita Ferreira de Sousa, Andrew Chesson

PMC · DOI: 10.2903/j.efsa.2024.8702 · 2024-04-08

## TL;DR

This paper evaluates the safety of a food enzyme preparation from a non-genetically modified bacterium used to produce a speciality carbohydrate, but the assessment could not be completed due to insufficient data.

## Contribution

The novelty lies in the evaluation of a new food enzyme preparation from Microbacterium foliorum for producing D-allulose, though the assessment was incomplete.

## Key findings

- The enzyme preparation is derived from non-genetically modified Microbacterium foliorum strain SYG27B.
- The enzyme is used to convert fructose into D-allulose.
- The assessment could not be completed due to inability to establish identity and characterize hazards.

## Abstract

This assessment addresses a food enzyme preparation consisting of the immobilised non‐viable cells of the non‐genetically modified bacterium identified by the applicant (Samyang Corporation) as Microbacterium foliorum strain SYG27B. This strain produces the enzyme D‐psicose 3‐epimerase (EC 5.1.3.30). The food enzyme preparation is used for the isomerisation of fructose to produce the speciality carbohydrate D‐allulose (synonym D‐psicose). Since the hazard identification and characterisation could not be made and the identity of the production organism could not be established, the Panel was unable to complete the assessment of this food enzyme preparation containing D‐psicose 3‐epimerase.

## Linked entities

- **Chemicals:** fructose (PubChem CID 5984), D-allulose (PubChem CID 441036), D-psicose (PubChem CID 441036)
- **Species:** Microbacterium foliorum (taxon 104336)

## Full-text entities

- **Chemicals:** D-allulose (MESH:C003243), fructose (MESH:D005632), carbohydrate (MESH:D002241)
- **Species:** Microbacterium foliorum (species) [taxon 104336]

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Source: https://tomesphere.com/paper/PMC11000130