# A Case Report of Malignant Mesenchymal Tumor Presenting As Anterior Thigh Swelling: A Diagnostic Challenge

**Authors:** Jayashree Rey, Samarth Shukla, Sourya Acharya, Pravin Gadkari, Sapna Sihag

PMC · DOI: 10.7759/cureus.55669 · Cureus · 2024-03-06

## TL;DR

A 64-year-old man with a thigh swelling was diagnosed with a rare malignant mesenchymal tumor after initial misdiagnosis, highlighting the need for thorough evaluation in similar cases.

## Contribution

This case report highlights diagnostic challenges and emphasizes the importance of histopathological confirmation in atypical soft tissue sarcoma presentations.

## Key findings

- Initial misdiagnosis led to worsening of the patient's condition.
- MRI and biopsy confirmed a malignant mesenchymal tumor compressing adjacent muscles.
- The case emphasizes the need for thorough evaluation in managing soft tissue sarcomas with comorbidities.

## Abstract

This case report describes the presentation, diagnostic challenges, and management of a 64-year-old male with a malignant mesenchymal tumor presenting as a swelling in the anterior thigh. Despite initial misdiagnosis and treatment at a local hospital, the swelling worsened, leading to referral to a specialized hospital. Further investigations, including blood tests, ultrasonography (USG), and MRI, revealed a large solid cystic lesion compressing adjacent muscles, indicative of soft tissue sarcoma (STS). A skin biopsy confirmed the diagnosis of a malignant mesenchymal tumor. The patient, also suffering from hypertension and diabetes mellitus, was subsequently referred to the oncology department for further management. This case underscores the importance of thorough evaluation and histopathological confirmation for accurate diagnosis and management of STS, particularly in the context of atypical presentations and comorbidities.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015), soft tissue sarcoma (MONDO:0018078)

## Full-text entities

- **Diseases:** STS (MESH:D012509), Malignant Mesenchymal Tumor (MESH:C535700), diabetes mellitus (MESH:D003920), Swelling (MESH:D004487), hypertension (MESH:D006973), swelling in the anterior thigh (MESH:D020759)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10997384/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC10997384/full.md

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Source: https://tomesphere.com/paper/PMC10997384