# Benign to Malignant Hepatic Lesion Transformation in Abernethy Malformation

## TL;DR

This paper reports a rare case of a liver condition leading to the transformation of a benign tumor into a malignant one.

## Contribution

The novelty lies in documenting the progression from benign to malignant liver lesions in Abernethy malformation.

## Key findings

- Abernethy malformation can lead to focal nodular hyperplasia.
- The benign tumor progressed to hepatocellular carcinoma in the reported case.
- This case highlights the potential for malignant transformation in this rare condition.

## Abstract

Abernethy malformation or congenital extrahepatic portosystemic shunt is an extremely rare condition whereby the portomesenteric blood drains into a systemic vein and bypasses the liver through a complete or partial shunt. Severe complications include hyperammonemia and encephalopathy, benign and malignant liver tumors, and hepatopulmonary syndrome. We describe a case where a female adult diagnosed with congenital extrahepatic portosystemic shunt subsequently developed focal nodular hyperplasia and then hepatocellular carcinoma.