Oncocytic Carcinoma with Liver Metastasis: Unusual Treatment Strategies and Clinical Insights—A Case Report and Review of the Literature

TL;DR

A rare case of pancreatic oncocytic carcinoma with liver metastasis showed a successful response to a combination of immunotherapy and tyrosine kinase inhibitors.

Contribution

The paper presents a novel therapeutic approach using combined immunotherapy and tyrosine kinase inhibitors for a rare pancreatic tumor.

Findings

The tumor resembled renal cell carcinoma but had no renal involvement.

The patient showed a sustained response to combined immunotherapy and tyrosine kinase inhibitors.

The case provides insights into the management of rare pancreatic oncocytic tumors.

Abstract

We report a distinctive case of malignant oncocytic carcinoma originating in the pancreas, an organ rarely associated with such tumours. We discuss the diagnostic journey, highlighting the tumour's resemblance to renal cell carcinoma but without renal involvement. A significant aspect of this case is the successful and sustained response to combined immunotherapy and tyrosine kinase inhibitors, demonstrating a potential therapeutic pathway for similar rare cases. This study contributes to a deeper understanding of pancreatic oncocytic tumours and their management.

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