# A Case Report of Brugada Syndrome Associated With Physical Trauma

**Authors:** Dinesh Nirmal, Nikola Stojanovic, Anandita Kishore, Shruthi Sivakumar, Asher Gorantla, Harshith Chandrakumar, Suzette Graham-Hill, Adam S Budzikowski

PMC · DOI: 10.7759/cureus.55557 · Cureus · 2024-03-05

## TL;DR

This case report describes a patient whose Brugada syndrome symptoms were linked to physical chest trauma and stress, highlighting the condition's unpredictable triggers.

## Contribution

The report presents a rare case where physical trauma and stress may have triggered Brugada syndrome symptoms.

## Key findings

- The patient showed transient EKG changes consistent with Brugada syndrome after chest trauma and stress.
- Physical trauma and stress may unmask or worsen Brugada syndrome, though causality is not proven.
- The case emphasizes the need to consider Brugada syndrome in patients with unexplained syncope or EKG changes.

## Abstract

Brugada syndrome is an autosomal dominant channelopathy that usually affects healthy young males without apparent structural heart disease. It is associated with a spectrum of variable and dynamic clinical manifestations, high risk of life-threatening ventricular arrhythmias, and sudden cardiac death. Our patient demonstrated transient and dynamic EKG changes of both type 1 (coved) and type 2 (saddleback) ST elevation, suggestive of the Brugada pattern that was associated with physical chest trauma and stressful situations. While common triggers like fever and certain drugs are well-recognized, this case illustrates the potential for physical stress and trauma to unmask or aggravate Brugada syndrome, albeit without definitive evidence for a causal link. Ultimately, this report underscores the importance of considering a broad differential diagnosis, including Brugada syndrome, in patients presenting with unexplained syncope or characteristic EKG changes, even when traditional triggers are absent.

## Linked entities

- **Diseases:** Brugada syndrome (MONDO:0015263)

## Full-text entities

- **Diseases:** heart disease (MESH:D006331), Brugada (MESH:D053840), autosomal dominant channelopathy (MESH:D053447), Trauma (MESH:D014947), fever (MESH:D005334), chest trauma (MESH:D013898), sudden cardiac death (MESH:D016757), ventricular arrhythmias (MESH:D001145), syncope (MESH:D013575)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10993764/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10993764/full.md

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Source: https://tomesphere.com/paper/PMC10993764