# Has the role of veno-arterial extracorporeal membrane oxygenation in patients with cardiogenic shock following acute myocardial infarction been fully determined? A case report

**Authors:** Kha Minh Nguyen, Hai Phuong Nguyen Tran, Vi Tuong Dang, Sy Van Hoang

PMC · DOI: 10.1093/ehjcr/ytae125 · European Heart Journal: Case Reports · 2024-03-12

## TL;DR

This case report shows that early use of VA ECMO in a patient with severe heart failure after a heart attack led to a successful recovery.

## Contribution

The report highlights a successful clinical outcome supporting early VA ECMO use in cardiogenic shock.

## Key findings

- VA ECMO initiation before intervention improved the patient's condition significantly.
- The patient was discharged in stable condition after 25 days with favorable 30-day outcomes.
- Teamwork and careful patient selection may enhance outcomes in such cases.

## Abstract

The persistent challenge of high mortality rates in acute myocardial infarction–induced cardiogenic shock endures notwithstanding advancements in the diagnosis and treatment of this disease over the past two decades. While recent studies present conflicting evidence on the efficacy of veno-arterial extracorporeal membrane oxygenation (VA ECMO), observational research supports the benefits of early VA ECMO initiation. However, the current lack of robust support from randomized clinical trials for VA ECMO use in this context highlights the ongoing uncertainty surrounding its effectiveness.

A 52-year-old male with sudden, intense chest pain was diagnosed with cardiogenic shock due to non–ST-elevation acute myocardial infarction at a local hospital. Initial treatment included aspirin, clopidogrel, and noradrenaline. Upon transfer to our hospital, the patient’s condition deteriorated, leading to acute respiratory distress and severe hypotension. Prior to emergent percutaneous coronary intervention, peripheral VA ECMO was initiated. Coronary angiography revealed left main coronary artery occlusion, and a successful intervention was performed. Post-intervention, the patient’s haemodynamic parameters significantly improved, and after 7 days, ECMO was successfully discontinued. The patient was discharged in stable condition after 25 days, with favourable outcomes persisting at the 30-day mark. Continuous monitoring is planned during outpatient follow-up.

The clinical case illustrates a successful treatment outcome achieved through teamwork by the heart team, supporting the efficacy of the VA ECMO pre–percutaneous coronary intervention approach. The careful selection of appropriate candidates and strategic initiation of VA ECMO may play a role in enhancing outcomes for individuals experiencing acute myocardial infarction complicated by challenging cardiogenic shock.

## Linked entities

- **Diseases:** cardiogenic shock (MONDO:0800175), acute myocardial infarction (MONDO:0004781)

## Full-text entities

- **Diseases:** chest pain (MESH:D002637), acute myocardial infarction (MESH:D009203), coronary artery occlusion (MESH:D054059), cardiogenic shock (MESH:D012770), respiratory distress (MESH:D012128), hypotension (MESH:D007022), acute (MESH:D000208)
- **Chemicals:** aspirin (MESH:D001241), noradrenaline (MESH:D009638), clopidogrel (MESH:D000077144)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10990060/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC10990060/full.md

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Source: https://tomesphere.com/paper/PMC10990060