# Anesthesia experience in an adult Silver-Russell syndrome: a case report

## TL;DR

This case report details the challenges of administering anesthesia to an adult with Silver-Russell syndrome and chronic respiratory failure.

## Contribution

The paper presents the first reported case of anesthesia use in an adult Silver-Russell syndrome patient.

## Key findings

- The patient experienced CO2 narcosis during anesthesia, indicating a risk for SRS patients with respiratory issues.
- Difficult airway management is necessary for SRS patients during the perioperative period.
- Chronic respiratory failure in SRS patients requires urgent intervention during anesthesia.

## Abstract

There are no reports of anesthesia use in adult patients with Silver-Russell syndrome (SRS). Here, we report our experience with anesthesia in an adult patient with SRS complicated by chronic respiratory failure.

A 33-year-old woman was clinically diagnosed with SRS. She had severe chronic respiratory failure, complicated by superior mesenteric artery syndrome. Percutaneous gastrostomy was scheduled for nutritional management under epidural anesthesia; however, soon after esophagogastroduodenoscopy was started, she lost consciousness and spontaneous respiration. The patient was urgently intubated and converted to general anesthesia. The end-tidal carbon dioxide tension was > 90 mmHg at intubation.

Adult SRS patients with chronic respiratory failure have a risk of CO2 narcosis. SRS also requires preparation for difficult airway management during the perioperative period.