# A Unique Case of Late Presentation Giant Lower Extremity Malignant Melanoma

**Authors:** Omar Al Zarkali, Amanda Marker, Lakhvir Kaur, Ana VanDerWall

PMC · DOI: 10.7759/cureus.55414 · Cureus · 2024-03-02

## TL;DR

This paper presents a rare case of a large melanoma that grew to an unusual size due to delayed treatment and was managed with a novel approach.

## Contribution

The paper introduces a unique case with features not previously documented and a novel treatment approach for giant melanoma.

## Key findings

- Giant melanomas are rare and often present with distant metastases.
- A literature review found only a few similar cases in the United States.
- The case was treated with a novel approach due to its unique features.

## Abstract

This case describes a unique presentation of a rare malignancy: giant melanoma. Due to the accessibility of healthcare in the United States, it is unusual for melanomas to grow to massive sizes without clinical intervention. In fact, an in-depth literature review elicited only a handful of similar cases. Giant malignant melanomas are typically defined by a cutoff size of no less than 10 cm in diameter. They often present with distant metastases and are highly invasive. Due to limited yet highly variable presentations, there is no standardized approach to treating this class of melanomas. We present a case with unique features not previously documented in similar cases that was ultimately treated with a novel approach.

## Linked entities

- **Diseases:** melanoma (MONDO:0005105)

## Full-text entities

- **Diseases:** malignancy (MESH:D009369), Giant Lower Extremity Malignant Melanoma (MESH:D008545), metastases (MESH:D009362)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10985282/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC10985282/full.md

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Source: https://tomesphere.com/paper/PMC10985282