# Hyperreactio Luteinalis: A Rare Phenomenon Complicating Gestational Trophoblastic Disease Presenting as Acute Abdomen in the Convalescence Period

**Authors:** Sachin Rathod, Neema Acharya, Amardeep Shanoo, Preeti Mishra, Anubha Dande

PMC · DOI: 10.7759/cureus.55382 · Cureus · 2024-03-02

## TL;DR

A rare gynecological condition called hydatidiform mole complicated by theca lutein cyst rupture presented as an acute abdomen in a young patient.

## Contribution

This case highlights the unusual presentation of hyperreactio luteinalis complicating gestational trophoblastic disease.

## Key findings

- A 17-year-old patient presented with acute abdomen due to ruptured theca lutein cysts following a molar pregnancy.
- Post-molar pregnancy outcomes are variable and understudied, with limited data from national databases and monocentric studies.

## Abstract

The hydatidiform mole is a rare gynaecological condition originating from trophoblastic cells, with an incidence of 1-3 per 1000 pregnancies. Theca lutein cysts (TLCs) and an invasive mole are rarely observed in association with a partial mole. This case describes an unusual case involving a 17-year-old primigravida at 11 weeks of gestation. She presented with abdominal pain and was diagnosed with a molar pregnancy with post-evacuation rupture of TLC, presenting as an acute abdomen, subsequently undergoing laparoscopy. Post-molar pregnancies exhibit a highly variable course, ranging from recurrent pregnancy loss and stillbirths to preterm deliveries and recurrent molar pregnancies. Few studies are available on obstetric outcomes after a molar pregnancy; most available data originate from national databases and monocentric research.

## Linked entities

- **Diseases:** hydatidiform mole (MONDO:0006248), gestational trophoblastic disease (MONDO:0018944)

## Full-text entities

- **Diseases:** invasive mole (MESH:D002820), preterm deliveries (MESH:D047928), mole (MESH:D009506), rupture (MESH:D012421), abdominal pain (MESH:D015746), Gestational Trophoblastic Disease (MESH:D031901), hydatidiform mole (MESH:D006828), stillbirths (MESH:D050497), TLCs (MESH:D013798), Abdomen (MESH:D000006), pregnancy loss (MESH:D000022)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10984135/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC10984135/full.md

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Source: https://tomesphere.com/paper/PMC10984135