# A Case Report of Dermatofibrosarcoma Protuberans and Refractory Hypomagnesemia: Unveiling a Paraneoplastic Syndrome

## TL;DR

This case report explores a rare connection between a skin tumor and low magnesium levels, suggesting a paraneoplastic syndrome.

## Contribution

The paper presents a novel case linking DFSP with refractory hypomagnesemia as a paraneoplastic syndrome.

## Key findings

- A 66-year-old female with DFSP exhibited persistent hypomagnesemia.
- Magnesium correction resolved the patient's symptoms and led to discharge.
- The case suggests a paraneoplastic syndrome linking DFSP and hypomagnesemia.

## Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive soft tissue sarcoma of the skin. DFSP typically presents as an asymptomatic, firm plaque in its earliest stage, gradually enlarging over months to years. This case report delineates a singular instance involving a 66-year-old female patient previously diagnosed with and treated for DFSP. The individual presented with a recurrent history of hospital admissions, manifesting symptoms of loose stools, generalised weakness, and diminished appetite. Investigations revealed persistent hypomagnesemia. The patient was treated with magnesium correction. Eventually, all complaints were resolved, and the patient was discharged satisfactorily. This case report aims to elucidate an exceptional correlation between DFSP and hypomagnesemia, characterised as its paraneoplastic syndrome (PNS). This study intends to comprehensively outline the clinical manifestations, diagnostic approaches, and therapeutic interventions pertaining to this distinct association.