# A Case of Severely Impaired Consciousness and Convulsions From Attempted Suicide by Ingesting Triflumizole Emulsion: Clinical Features and Literature Review

## TL;DR

A 70-year-old man attempted suicide by ingesting a fungicide called Triflumizole, leading to severe symptoms like impaired consciousness and convulsions.

## Contribution

This is the first documented case of acute oral intoxication with Triflumizole emulsion in humans.

## Key findings

- The patient showed severe consciousness disturbance and convulsions after ingesting Triflumizole emulsion.
- Symptomatic treatment, mechanical ventilation, and antiepileptic drugs led to full recovery without long-term effects.
- The case highlights the potential toxicity of Triflumizole in humans despite its agricultural use.

## Abstract

Triflumizole (TFZ) is a fungicide widely used in agriculture to prevent fungal infections of fruits and vegetables. Although it is considered safe for humans and animals, its toxicity profile in humans remains largely unexplored. Here, we describe a case where an individual experienced symptoms suggestive of intoxication after ingesting TFZ emulsion.

A 70-year-old man ingested TFZ emulsion (Trifumin emulsionTM) and alcohol in an attempt to commit suicide. He developed a severe disturbance of consciousness, which was not explained by the estimated blood alcohol concentration, and experienced convulsions. We managed this patient with symptomatic treatment, temporary mechanical ventilation, and antiepileptic drugs. He subsequently recovered without any sequelae.

We present the first case of acute oral intoxication with TFZ emulsion. Moreover, we review the literature on TFZ-induced organ dysfunction and discuss the possible mechanisms and management of this condition.