# Targeted Six-Week Intensive Physiotherapy for a Case of Tuberculous Meningitis With a Syndrome of Inappropriate Antidiuretic Hormone Secretion

**Authors:** Arjavi A Pakhan, Raghuveer Raghumahanti

PMC · DOI: 10.7759/cureus.55214 · Cureus · 2024-02-29

## TL;DR

This case report shows how a six-week intensive physiotherapy program improved the quality of life and functional abilities of a patient with severe tuberculous meningitis.

## Contribution

The study demonstrates the effectiveness of early and targeted physiotherapy in managing complications of tuberculous meningitis.

## Key findings

- The patient showed significant improvement in muscle strength and independence in daily activities after six weeks of physiotherapy.
- Early physiotherapy intervention helped maintain joint integrity and improve postural strength in a TBM patient.
- The program enhanced the patient's ability to perform activities of daily living and swallow independently.

## Abstract

Tuberculous meningitis (TBM) is a severe form of extrapulmonary tuberculosis (TB) characterized by the invasion of Mycobacterium tuberculosis into the meninges surrounding the brain and spinal cord. It triggers an intense inflammatory response, leading to neurological complications if not promptly and adequately managed. TBM often precipitates muscle weakness, neurological deficits, respiratory challenges, swallowing difficulties, joint contractures, and pain. Physiotherapy intervention is essential in treating these problems by personalized treatment strategies and treatment plans to enhance muscle strength, motor control, coordination, and overall mobility. This case report aims to highlight the significant role of physiotherapy in improving the quality of life (QOL) and functional abilities of patients with TBM. The current case report reviews the case of a 73-year-old male who presented with complaints of generalized weakness and difficulty in swallowing. The patient had a history of fever for the last six months. Magnetic resonance imaging (MRI) and high-resolution computed tomography (HRCT) diagnosed the case as TBM with miliary TB. Six weeks of targeted intensive rehabilitation program was designed according to the patient's impairments initiated from the intensive care unit (ICU) phase. The main goals of physiotherapy were to start early bed mobility, maintain joint integrity, improve postural strength and swallowing, and make the patient independent in transfer and activities of daily living (ADLs). After a six-week intensive physiotherapy (TIP-6) program, the patient exhibited significant improvements in muscle strength and independence in ADLs. This case highlights the critical role of physiotherapy in enhancing the QOL and functional abilities of patients with severe TB-related conditions.

## Linked entities

- **Diseases:** tuberculous meningitis (MONDO:0006042)

## Full-text entities

- **Diseases:** extrapulmonary tuberculosis (MESH:D000092225), TB (MESH:D014376), fever (MESH:D005334), neurological deficits (MESH:D009461), difficulty in swallowing (MESH:D003680), joint contractures (MESH:D003286), inflammatory (MESH:D007249), pain (MESH:D010146), neurological complications (MESH:D002493), miliary TB (MESH:D014391), TBM (MESH:D014390), muscle weakness (MESH:D018908), Antidiuretic Hormone (MESH:D007177)
- **Species:** Mycobacterium tuberculosis (species) [taxon 1773], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC10981514/full.md

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Source: https://tomesphere.com/paper/PMC10981514