# Atypical Manifestation of Adult Polycystic Kidney Disease in an Elderly Individual

**Authors:** Oxana Ushakova, Keyvan Ravakhah

PMC · DOI: 10.7759/cureus.55072 · Cureus · 2024-02-27

## TL;DR

This paper discusses a rare case of adult polycystic kidney disease in an elderly person, highlighting its unusual presentation and complications.

## Contribution

The novelty lies in describing an atypical manifestation of ADPKD in an elderly individual, emphasizing unique clinical features.

## Key findings

- ADPKD Type 2 is associated with later symptom onset and slower progression.
- Patients with ADPKD are at risk for multiple complications including kidney failure and aneurysms.
- Elderly individuals may present with atypical symptoms of ADPKD.

## Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is a rare genetic disease. Diagnosis of ADPKD is usually made by the number of renal cysts on the ultrasound for each age category. There are two types of ADPKD, and the patients with the second type have later onset of symptoms, with slower disease progression than in the first type. These patients are typically at risk of recurrent urinary tract infections, hemorrhage and rupture of cysts, end-stage renal disease, calculi, liver/pancreatic cysts, and brain aneurysm development.

## Linked entities

- **Diseases:** Autosomal dominant polycystic kidney disease (MONDO:0004691), end-stage renal disease (MONDO:0004375)

## Full-text entities

- **Diseases:** hemorrhage and rupture of (MESH:D012421), cysts (MESH:D003560), urinary tract infections (MESH:D014552), ADPKD (MESH:D016891), calculi (MESH:D002137), brain aneurysm (MESH:D002532), genetic disease (MESH:D030342), Polycystic Kidney Disease (MESH:D007690), liver/pancreatic cysts (MESH:D010181), end-stage renal disease (MESH:D007676)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10977902/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC10977902/full.md

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Source: https://tomesphere.com/paper/PMC10977902