# Potential Sexual Transmission of Antifungal-Resistant Trichophyton indotineae

**Authors:** Stephanie Spivack, Jeremy A.W. Gold, Shawn R. Lockhart, Priyanka Anand, Laura A.S. Quilter, Dallas J. Smith, Briana Bowen, Jane M. Gould, Ahmed Eltokhy, Ahmed Gamal, Mauricio Retuerto, Thomas S. McCormick, Mahmoud A. Ghannoum

PMC · DOI: 10.3201/eid3004.240115 · Emerging Infectious Diseases · 2024-04-01

## TL;DR

A woman in Pennsylvania contracted a rare antifungal-resistant fungal infection, possibly through sexual contact, which responded to itraconazole.

## Contribution

First reported case of potential sexual transmission of antifungal-resistant Trichophyton indotineae.

## Key findings

- Trichophyton indotineae caused tinea genitalis in an immunocompetent woman.
- The infection was resistant to terbinafine but improved with itraconazole.
- The case suggests possible sexual transmission of the fungus.

## Abstract

We describe a case of tinea genitalis in an immunocompetent woman in Pennsylvania, USA. Infection was caused by Trichophyton indotineae potentially acquired through sexual contact. The fungus was resistant to terbinafine (first-line antifungal) but improved with itraconazole. Clinicians should be aware of T. indotineae as a potential cause of antifungal-resistant genital lesions.

## Linked entities

- **Chemicals:** terbinafine (PubChem CID 1549008), itraconazole (PubChem CID 55283)
- **Species:** Trichophyton indotineae (taxon 2739387)

## Full-text entities

- **Diseases:** Infection (MESH:D007239), genital lesions (MESH:D000091662), tinea genitalis (MESH:D014005)
- **Species:** Trichophyton indotineae (species) [taxon 2739387], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10977831/full.md

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Source: https://tomesphere.com/paper/PMC10977831