# Case of Human Orthohantavirus Infection, Michigan, USA, 2021

## TL;DR

A 65-year-old woman in Michigan was infected with orthohantavirus, a rare occurrence outside the U.S. southwest, and the virus was linked to local rodents.

## Contribution

This is the first reported case of orthohantavirus infection in Michigan, with phylogeographic evidence linking the virus to local rodent populations.

## Key findings

- Orthohantavirus infection was confirmed in a 65-year-old woman from Michigan.
- Partial viral fragments from the patient matched those from rodents captured near her location.
- The case expands the geographic understanding of orthohantavirus transmission in the U.S.

## Abstract

Orthohantaviruses cause hantavirus cardiopulmonary syndrome; most cases occur in the southwest region of the United States. We discuss a clinical case of orthohantavirus infection in a 65-year-old woman in Michigan and the phylogeographic link of partial viral fragments from the patient and rodents captured near the presumed site of infection.