# Novel Oral Poliovirus Vaccine 2 Safety Evaluation during Nationwide Supplemental Immunization Activity, Uganda, 2022

## TL;DR

A new oral polio vaccine was tested for safety in Uganda in 2022 and found to be safe.

## Contribution

The study confirms the safety of a novel oral poliovirus vaccine type 2 during a large-scale immunization campaign.

## Key findings

- No safety signals were detected using passive and active surveillance methods.
- The vaccine was safely administered during a nationwide supplemental immunization activity.

## Abstract

Given its enhanced genetic stability, novel oral poliovirus vaccine type 2 was deployed for type 2 poliovirus outbreak responses under World Health Organization Emergency Use Listing. We evaluated the safety profile of this vaccine. No safety signals were identified using a multipronged approach of passive and active surveillance.