# Non-Invasive Device-Mediated Drug Delivery to the Brain across the Blood–Brain Barrier

**Authors:** Toshihiko Tashima, Nicolas Tournier

PMC · DOI: 10.3390/pharmaceutics16030361 · Pharmaceutics · 2024-03-05

## Full-text entities

- **Genes:** ABCB1 (ATP binding cassette subfamily B member 1) [NCBI Gene 5243] {aka ABC20, CD243, CLCS, ENPAT, GP170, MDR1}, APP (amyloid beta precursor protein) [NCBI Gene 351] {aka AAA, ABETA, ABPP, AD1, APPI, CTFgamma}, ANPEP (alanyl aminopeptidase, membrane) [NCBI Gene 290] {aka AP-M, AP-N, APN, CD13, GP150, LAP1}, TFRC (transferrin receptor) [NCBI Gene 7037] {aka CD71, IMD46, T9, TFR, TFR1, TR}, Tfrc (transferrin receptor) [NCBI Gene 22042] {aka 2610028K12Rik, CD71, E430033M20Rik, Mtvr1, TFR, TFR1}, RTN4R (reticulon 4 receptor) [NCBI Gene 65078] {aka NGR, NOGOR, NgR1}, MAPT (microtubule associated protein tau) [NCBI Gene 4137] {aka DDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1}, TF (transferrin) [NCBI Gene 7018] {aka HEL-S-71p, PRO1557, PRO2086, TFQTL1}, IDS (iduronate 2-sulfatase) [NCBI Gene 3423] {aka ID2S, MPS2, SIDS}, Bace1 (beta-site APP cleaving enzyme 1) [NCBI Gene 23821] {aka ASP2, Bace}, Sdc2 (syndecan 2) [NCBI Gene 15529] {aka 4833414L08Rik, Hspg1, Synd2, syndecan-2}
- **Diseases:** brain diseases (MESH:D001927), central nervous system (CNS) diseases (MESH:D002493), brain cancers (MESH:D001932), cancer (MESH:D009369), injury to people or property (MESH:C000719191), AD (MESH:D000544), neurodegenerative diseases (MESH:D019636), MPS II (MESH:D016532), glioma (MESH:D005910), PD (MESH:D010300)
- **Chemicals:** doxorubicin (MESH:D004317), lecithin (MESH:D054709), PLGA (MESH:D000077182), polymers (MESH:D011108), Asn-Gly-Arg (MESH:C526428), Memantine (MESH:D008559), lecanemab (MESH:C000612089), silicon (MESH:D012825), PLA (MESH:C033616), heparan sulfate (MESH:D006497), chitosan (MESH:D048271), amine (MESH:D000588), Fitc-dextran (MESH:C015219), aducanumab (MESH:C000600266), rotigotine (MESH:C047508), Arg-Gly-Asp (MESH:C047981), N (MESH:D009584), DAS peptide (-)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** THPs — Mesocricetus auratus (Golden hamster), Hamster neoplasm, Cancer cell line (CVCL_Y446), hCMEC/D3 — Homo sapiens (Human), Transformed cell line (CVCL_U985)

## Full text

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## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC10974733/full.md

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Source: https://tomesphere.com/paper/PMC10974733