# Osteosynthesis of an intertrochanteric fracture on osteopetrosis A case report

**Authors:** K. Tabbak, M.A. Kharroube, F. Lamnaouar, C. Elkassimi, A. Rafaoui, M. Rafai

PMC · DOI: 10.1016/j.ijscr.2024.109568 · International Journal of Surgery Case Reports · 2024-03-20

## TL;DR

This case report describes the successful surgical treatment of a trochanteric fracture in a young man with osteopetrosis, a rare bone disease.

## Contribution

The paper highlights effective surgical techniques and principles for managing fractures in osteopetrosis patients.

## Key findings

- Fracture healed well 24 months after surgery with no activity restrictions.
- Anatomic plate fixation is an effective treatment for trochanteric fractures in osteopetrosis.
- Following specific surgical principles reduces complications in osteopetrotic bone.

## Abstract

Osteopetrosis is a rare hereditary disease that can be transmitted in an autosomal recessive or autosomal dominant.

Here, we report a case of trochanteric fracture in an 18-year-old boy with an anatomical plate. At the last follow-up, 24 months after surgery, the fracture had healed well, and the patient was not restricted in his activities.

Osteopetrosis is a rare bone disease that is mainly caused by osteoclast dysfunction. It results from a remodelling defect that leads to hypermineralization of the skeleton, resulting in bone fragility. Both surgical and nonsurgical management have advantages and disadvantages. Thus, open reduction and anatomic plate fixation remain effective management modalities for trochanteric fractures in osteopetrosis patients.

For our patient and as described in the literature, the complication rate decreases as some principles are respected with better consolidation of the osteoporotic fracture.

•Osteopetrosis due to osteoclast dysfunction. result is a remodeling defect that leads to hypermineralization of the skeleton, resulting in bone fragility.•Operative intervention, presents many technical challenges•some principles are to respect in the osteosynthesis of fractures in osteopetrotic bone to avoid complications

Osteopetrosis due to osteoclast dysfunction. result is a remodeling defect that leads to hypermineralization of the skeleton, resulting in bone fragility.

Operative intervention, presents many technical challenges

some principles are to respect in the osteosynthesis of fractures in osteopetrotic bone to avoid complications

## Linked entities

- **Diseases:** osteopetrosis (MONDO:0017198)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** fracture (MESH:D050723), intertrochanteric fracture (MESH:D006620), osteoclast dysfunction (MESH:D001862), skeleton (MESH:D000130), osteoporotic fracture (MESH:D058866), Osteopetrosis (MESH:D010022), bone fragility (MESH:C536063), hereditary disease (MESH:D030342), bone disease (MESH:D001847)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10972786/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC10972786/full.md

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Source: https://tomesphere.com/paper/PMC10972786