# Diffuse Large B-cell Lymphoma of the Ovaries Presenting With a Paraneoplastic Sclerotic Skin Lesion

## TL;DR

A teenage girl with a skin lesion was found to have rare ovarian lymphoma, which improved after treatment.

## Contribution

This case report highlights a rare association between paraneoplastic skin lesions and extranodal lymphoma.

## Key findings

- A 15-year-old female presented with a sclerotic skin lesion and was diagnosed with ovarian DLBCL.
- The skin lesion resolved after treatment with COP, along with improvement in the lymphoma.
- This case demonstrates a rare extranodal manifestation of lymphoma linked to a paraneoplastic skin lesion.

## Abstract

Paraneoplastic presentations are often the initial presenting symptom of a malignant process. A 15-year-old female presented with a progressively growing, sclerotic lesion of the neck restricting the range of motion. She was found to have bilateral ovarian tumors that proved to be diffuse large B-cell lymphoma (DLBCL). After starting cyclophosphamide, vincristine, and prednisone (COP), she had a rapid and complete resolution of the sclerotic lesion, as well as a favorable response to the neoplastic process. In this report, we present a very rare case of extranodal lymphoma associated with a paraneoplastic skin lesion.