# Information Theoretic Study of COVID-19 Genome

**Authors:** Philippe Jacquet

PMC · DOI: 10.3390/e26030223 · 2024-03-01

## TL;DR

This paper uses information theory to analyze the COVID-19 genome and compare it with other genomes to measure similarities.

## Contribution

The paper introduces a low-complexity joint complexity tool for genome comparison, more efficient than the Smith–Waterman algorithm.

## Key findings

- Joint complexity can effectively quantify genome similarities with lower computational cost.
- The method allows for large-scale genome comparisons due to its efficiency.
- The approach was applied to compare the COVID-19 genome with past and present genomes.

## Abstract

In this paper, we analyse the genome sequence of COVID-19 on a information point of view, and we compare that with past and present genomes. We use the powerful tool of joint complexity in order to quantify the similarities measured between the various potential parent genomes. The tool has a computing complexity of several orders of magnitude below the classic Smith–Waterman algorithm and would allow it to be used on a larger scale.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382)

## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10968974/full.md

---
Source: https://tomesphere.com/paper/PMC10968974