# Hepatic Diffuse Large B-cell Lymphoma: A Case Report and Review of Literature of Primary Liver Tumors

## TL;DR

A rare case of liver cancer called diffuse large B-cell lymphoma is reported, emphasizing its importance in diagnosing liver tumors.

## Contribution

This case report adds to the limited literature on hepatic diffuse large B-cell lymphoma and highlights its diagnostic challenges.

## Key findings

- A 45-year-old woman was diagnosed with hepatic diffuse large B-cell lymphoma via biopsy.
- The case underscores the need to consider this rare lymphoma in liver tumor differential diagnoses.
- Treatment typically includes chemotherapy, immunotherapy, and radiation therapy.

## Abstract

Liver tumors rank as the fourth most common cause of cancer. This case report highlights a 45-year-old female patient who presented persistent abdominal pain and no other symptoms. Initially, she was approached with a probable hepatitis of unknown origin, but her condition worsened rapidly. An endoscopic ultrasound was used to characterize the lesion, and a fine needle biopsy of the lesion was performed which revealed a diffuse large B-cell lymphoma that is CD20+ and Ki67+. Hepatic diffuse large B-cell lymphoma, as diagnosed in the patient, is a rare type of lymphoma that arises in the liver. The treatment usually involves chemotherapy, immunotherapy, and radiation therapy. However, the prognosis depends on the stage of the disease and the patient's overall health. This case reinforces the importance of considering hepatic diffuse large B-cell lymphoma in differential diagnosis for primary liver neoplasia.