The Top 50 Articles and Authors of the New Millennium in Psychiatry: A Bibliometric Analysis
John L Havlik, Sofía I Uranga, Megan S Lee, Seneca Magallanes, Syed Wahid, Taeho (Greg) Rhee

TL;DR
This study identifies the top 50 most cited articles and authors in psychiatry since 2000, highlighting trends and gaps in the field.
Contribution
The study provides a comprehensive bibliometric analysis of psychiatry in the new millennium, addressing a gap in subfield-focused research.
Findings
The United States contributed the highest number of psychiatric publications since 2000.
The American Journal of Psychiatry hosted eight of the top 50 most cited articles.
Female representation among top authors was limited, comprising 24% of first authors.
Abstract
The field of psychiatry faces significant challenges in the new millennium, marked by a surge in mental health diagnoses coupled with barriers to accessing adequate care. Despite obstacles, notable advancements have been achieved throughout the field, including the release of DSM-5, the introduction of esketamine, and the development of innovative assessment tools. This study aims to comprehensively analyze recent advances in psychiatry by examining the top 50 most cited articles and authors since 2000, addressing a gap in the literature left by previous subfield-focused bibliometric studies. Utilizing the Web of Science (WOS) database, this bibliometric analysis examined all publications in psychiatric journals from January 1, 2000, to September 18, 2022. The top 50 most cited articles and authors were identified and characterized based on various metrics, including times cited,…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
| Table | |||||||
| Rank | Times cited* | Publication type | Article title (as published) | Type of article | Author last name, first initials** | Journal | Year published |
| 1 | 15,001 | Article | Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication [ | Cross-sectional | Kessler, RC; Berglund, P; Walters, EE | Archives of General Psychiatry | 2005 |
| 2*** | 8,592 | Letter | Diagnostic and statistical manual of mental disorders [ | Commentary | Mittal, VA; Walker, EF | Psychiatry Research | 2011 |
| 3 | 5,559 | Article | Short screening scales to monitor population prevalences and trends in non-specific psychological distress [ | New measure | Kessler, RC; Andrews, G; Zaslavsky, AM | Psychological Medicine | 2002 |
| 4 | 5,184 | Review | The validity of the Hospital Anxiety and Depression Scale. An updated literature review [ | Literature review | Bjelland, I; Dahl, AA; Neckelmann, D | Journal of Psychosomatic Research | 2002 |
| 5 | 4,078 | Article | Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC) [ | New measure | Connor, KM; Davidson, JR | Depression and Anxiety | 2003 |
| 6 | 4,033 | Review | The endophenotype concept in psychiatry: etymology and strategic intentions [ | Review | Gottesman, II; Gould, TD | American Journal of Psychiatry | 2003 |
| 7 | 4,026 | Article | Psychometric properties of the strengths and difficulties questionnaire [ | Cross-sectional | Goodman, R | Journal of the American Academy of Child and Adolescent Psychiatry | 2001 |
| 8 | 3,745 | Editorial Material | Research Domain Criteria (RDoC): toward a new classification framework for research on mental disorders [ | Clnical classification | Insel T; Cuthbert, B; Wang, P | American Journal of Psychiatry | 2010 |
| 9 | 3,438 | Article | The "Reading the Mind in the Eyes" test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism [ | New diagnostic tool | Baron-Cohen, S; Wheelwright, S; Plumb, I | Journal of Child Psychology and Psychiatry | 2001 |
| 10 | 3,336 | Article | Lifetime prevalence of mental disorders in U.S. adolescents: results from the national comorbidity survey replication-adolescent supplement (NCS-A) [ | Cross-sectional | Merikangas, KR; He, JP; Swendsen, SA | Journal of the American Academy of Child and Adolescent Psychiatry | 2010 |
| 11 | 3,240 | Article | The worldwide prevalence of ADHD: a systematic review and metaregression analysis [ | systematic review | Polanczyk, G; de Lima, MS; Rohde, LA | American Journal of Psychiatry | 2007 |
| 12 | 3,183 | Article | Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication [ | Cross-sectional | Kessler, RC; Chiu, WT; Walters, EE | Archives of General Psychiatry | 2005 |
| 13 | 3,175 | Review | Neurocircuitry of addiction [ | Literature review | Koob, GF; Volkow, ND | Neuropsychopharmacology | 2010 |
| 14 | 3,134 | Article | The PHQ-9: a new depression diagnostic and severity measure [ | RCT | Kroenke, K; Spitzer, RL, Williams, JB | Psychiatric Annals | 2002 |
| 15 | 3,068 | Article | Screening for serious mental illness in the general population [ | New measure | Kessler, RC; Barker, PR; Zaslavasky, AM | Archives of General Psychiatry | 2003 |
| 16 | 3,057 | Article | Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report [ | RCT | Rush, AJ; Trivedi, MH; Fava, M | American Journal of Psychiatry | 2006 |
| 17 | 2,946 | Review | The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) [ | New measure | Kessler, RC; Ustun, TB | International journal of methods in psychiatric research | 2004 |
| 18 | 2,883 | Article | The prevalence and correlates of eating disorders in the national comorbidity survey replication [ | Cross-sectional | Hudson, JI; Hiripi, E; Kessler, RC | Biological Psychiatry | 2007 |
| 19 | 2,882 | Review | Parkinson's disease: clinical features and diagnosis [ | Jankovic, J | Journal of Neurology Neurosurgery and Psychiatry | 2008 | |
| 20 | 2,879 | Article | A meta-analysis of cytokines in major depression [ | Meta-analysis | Dowlati, Y; Herrmann, N; Lanctot, KL | Biological Psychiatry | 2010 |
| 21 | 2,573 | Article | NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses [ | New measure | Shaffer, D.; Fisher, P; Schwab-Stone, ME | Journal of the American Academy of Child and Adolescent Psychiatry | 2000 |
| 22 | 2,559 | Article | Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science [ | Literature review | Holmes, EA; O'Connor, RC ; Bullmore, E | Lancet Psychiatry | 2020 |
| 23 | 2,548 | Article | Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice [ | RCT | Trivedi, MH; Rush, AJ; Fava, M | American Journal of Psychiatry | 2006 |
| 24 | 2,531 | Article | Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change [ | Statistical method | Pruessner, JC; Kirschbaum, C; Hellhammer, DH | Psychoneuroendocrinology | 2003 |
| 25 | 2,517 | Article | Prevalence and development of psychiatric disorders in childhood and adolescence [ | Cross-sectional | Costello, E; Mustillo, S; Angold, A | Archives of General Psychiatry | 2003 |
| 26 | 2,396 | Article | The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication [ | Cross-sectional | Kessler, RC; Adler, L; Zaslavsky, A | American Journal of Psychiatry | 2006 |
| 27 | 2,380 | Review | A neurotrophic model for stress-related mood disorders [ | Literature review | Duman, RS; Monteggia, LM | Biological Psychiatry | 2006 |
| 28 | 2,327 | Review | Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression [ | Literature review | Miller, AH; Maletic, V; Raison, CL | Biological Psychiatry | 2009 |
| 28 | 2,327 | Article | The 16-item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression [ | New measure | Rush, AJ; Trivedi, MH; Keller, MB | Biological Psychiatry | 2003 |
| 30 | 2,316 | Review | Overweight, obesity, and depression a systematic review and meta-analysis of longitudinal studies [ | Systematic review and meta-analysis | Luppino, FS; de Wit, LM; Zitman, FG | Archives of General Psychiatry | 2010 |
| 31 | 2,298 | Review | The enduring effects of abuse and related adverse experiences in childhood - a convergence of evidence from neurobiology and epidemiology [ | Cross-sectional | Anda, RF; Felitti, VJ; Giles, WH | European Archives of Psychiatry and Clinical Neuroscience | 2006 |
| 32 | 2,292 | Article | The NimStim set of facial expressions: judgments from untrained research participants [ | New dataset | Tottenham, N; Tanaka, JW; Nelson, C | Psychiatry Research | 2009 |
| 33 | 2,269 | Article | A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression [ | RCT | Zarate, CA; Singh, JB; Manji, HK | Archives of General Psychiatry | 2006 |
| 33 | 2,269 | Article | Antidepressant effects of ketamine in depressed patients [ | RCT | Berman, RM; Cappiello, A; Krystal, JH | Biological Psychiatry | 2000 |
| 35 | 2,262 | Article | Mindfulness-based stress reduction and health benefits - a meta-analysis [ | meta-analysis | Grossman, P; Niemann, L; Walach, H | Journal of Psychosomatic Research | 2004 |
| 36 | 2,253 | Review | What is cognitive reserve? Theory and research application of the reserve concept [ | Review | Stern, Y | Journal of the International Neuropsychological Society | 2002 |
| 37 | 2,198 | Review | Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review [ | Review and meta-analysis | Willcutt, EG; Doyle, AE; Pennington, BF | Biological Psychiatry | 2005 |
| 37 | 2,198 | Review | Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"? [ | Review and meta-analysis | Green, MF; Kern, RS; Mintz, J | Schizophrenia Bulletin | 2000 |
| 39 | 2,196 | Article | The size and burden of mental disorders and other disorders of the brain in Europe 2010 [ | Cross-sectional | Wittchen, HU; Jacobi, F; Steinhausen, HC | European Neuropsychopharmacology | 2011 |
| 40 | 2,175 | Article | The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies With adolescents and adults [ | New measure | Posner, K; Brown, GK; Mann, JJ | American Journal of Psychiatry | 2011 |
| 41 | 2,142 | Review | The reward circuit: linking primate anatomy and human imaging [ | Review | Haber, SN; Knutson, B | Neuropsychopharmacology | 2010 |
| 42 | 2,133 | Review | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia [ | Meta-analysis | Etkin, A; Wager, TD | American Journal of Psychiatry | 2007 |
| 43 | 2,131 | Article | Testing mediational models with longitudinal data: questions and tips in the use of structural equation modeling [ | Statistical method | Cole, DA; Maxwell, SE | Journal of Abnormal Psychology | 2003 |
| 44 | 2,129 | Article | The PHQ-8 as a measure of current depression in the general population [ | Cross-sectional | Kroenke, K; Strine, TW; Mokdad, AH | Journal of Affective Disorders | 2009 |
| 45 | 2,068 | Review | The amygdala: vigilance and emotion [ | Review | Davis, M; Whalen, PJ | Molecular Psychiatry | 2001 |
| 46 | 2,062 | Article | The Patient Health Questionnaire somatic, anxiety, and depressive symptom scales: a systematic review [ | Systematic review | Kroenke, K; Spitzer, RL; Lowe, B | General Hospital Psychiatry | 2010 |
| 47 | 2,055 | Article | The psychological impact of the COVID-19 epidemic on college students in China [ | Cross-sectional | Cao, WJ; Fang, ZW; Zheng, JZ | Psychiatry Research | 2020 |
| 48 | 2,016 | Article | Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders - results from the national epidemiologic survey on alcohol and related conditions [ | Cross-sectional | Grant, BF; Stinson, FS; Kaplan, K | Archives of General Psychiatry | 2004 |
| 49 | 1,974 | Article | The Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5): development and initial psychometric evaluation [ | Cross-sectional | Blevins, CA; Weathers, FW; Domino, JL | Journal of Traumatic Stress | 2015 |
| 50 | 1,964 | Article | Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample [ | Cross-sectional | Simonoff, E; Pickles, A; Baird, G | Journal of the American Academy of Child and Adolescent Psychiatry | 2008 |
| Rank | Author last name, initial(s) | Times cited | Most cited article | Year published, most cited article | Avg. # most cited article was cited/year | Number of publications (y) | H-index (z) | Institution, country | At top-40 NIH funded program? | Highest post-graduate degree(s) |
| 1 | Kessler, RC | 239,845 | Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication [ | 2005 | 829.3 | 1,134 | 229 | Harvard University, United States | yes | PhD |
| 2 | Mokdad, AH | 134,360 | Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the global burden of disease study 2017 [ | 2018 | 1312 | 626 | 135 | University of Washington, United States | no | PhD |
| 3 | Volkow, ND | 96,706 | Neurocircuitry of addiction [ | 2010 | 234.9 | 1245 | 150 | National Institutes of Health, United States | no | MD |
| 4 | Kroenke, K | 96,081 | The PHQ-9 - validity of a brief depression severity measure [ | 2001 | 941 | 387 | 101 | Indiana University, United States | no | MD |
| 5 | Koob, GF | 92,437 | Neurocircuitry of addiction [ | 2001 | 234.9 | 1037 | 156 | National Institutes of Health, United States | yes | PhD |
| 6 | Wittchen, HU | 77,406 | Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States - results from the National-Comorbidity-Survey [ | 1994 | 313.4 | 967 | 127 | Ludwig Maximilian University of Munich, Germany | no | PhD |
| 7 | Williams, JBW | 70,938 | The PHQ-9 - validity of a brief depression severity measure [ | 2001 | 941 | 243 | 53 | Columbia University, United States | yes | PhD |
| 8 | Stern, Y | 67,024 | Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease [ | 2011 | 339.8 | 527 | 128 | Columbia University, United States | yes | PhD |
| 9 | Rush, AJ | 66,835 | The epidemiology of major depressive disorder - Results from the National Comorbidity Survey Replication (NCS-R). [ | 2003 | 274 | 588 | 119 | Duke University, United States | yes | MD |
| 10 | Grant, BF | 62,628 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 [ | 2012 | 634.8 | 354 | 108 | National Institutes of Health, United States | no | PhD |
| 11 | Duman, RS | 59,793 | Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants [ | 2003 | 157.2 | 449 | 120 | Yale University, United States | yes | PhD |
| 12 | Mann, JJ | 57,895 | The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults [ | 2011 | 184.2 | 997 | 121 | Columbia University, United States | yes | MD |
| 13 | Fava, M | 56,676 | Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report [ | 2006 | 179.6 | 1071 | 110 | Harvard University, United States | yes | MD |
| 14 | Walters, EE | 50,856 | Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication [ | 2005 | 829.3 | 61 | 44 | University of Southern California, United States | yes | MS |
| 15 | Krystal, JH | 49,167 | Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans - psychotomimetic, perceptual, cognitive, and neuroendocrine responses [ | 1994 | 84.87 | 754 | 117 | Yale University, United States | yes | MD |
| 16 | Wager, TD | 48,804 | The unity and diversity of executive functions and their contributions to complex "frontal lobe" tasks: a latent variable analysis [ | 2000 | 369.1 | 357 | 84 | Dartmouth College, Unites States | yes | PhD |
| 17 | Zaslavasky, AM | 46,964 | Short screening scales to monitor population prevalences and trends in non-specific psychological distress [ | 2002 | 268.8 | 431 | 88 | Harvard University, United States | yes | PhD |
| 18 | Baron-Cohen, S | 44,994 | Autism [ | 2014 | 131.4 | 244 | 96 | University of Cambridge, England | no | PhD |
| 19 | Trivedi, M H | 44,882 | Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report [ | 2006 | 179.6 | 807 | 98 | The University of Texas Southwestern Medical Center, United States | yes | MD |
| 20 | Insel T | 44,443 | The Genotype-Tissue Expression (GTEx) project [ | 2013 | 396.6 | 347 | 100 | National Institutes of Health, United States | no | MD |
| 21 | Merikangas, KR | 39,841 | The epidemiology of major depressive disorder - Results from the National Comorbidity Survey Replication (NCS-R) [ | 2003 | 274 | 381 | 83 | National Institutes of Health, United States | no | PhD |
| 22 | Löwe, B | 35,373 | A brief measure for assessing generalized anxiety disorder - The GAD-7 [ | 2006 | 719.7 | 344 | 55 | University of Heidelberg, Germany | no | MD |
| 23 | Anda, RF | 35,232 | Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults - the adverse childhood experiences (ACE) study [ | 1998 | 350 | 139 | 69 | Centers for Disease Control and Prevention, United States | no | MD |
| 24 | Costello, E | 35,100 | Prevalence and development of psychiatric disorders in childhood and adolescence [ | 2003 | 122.5 | 211 | 97 | Duke University, United States | yes | PhD |
| 25 | Giles, WH | 31,927 | Prevalence of the metabolic syndrome among US adults - findings from the Third National Health and Nutrition Examination Survey [ | 2002 | 221.3 | 237 | 77 | University of Illinois at Chicago, United States | no | MD |
| 26 | Wang, PS | 30,936 | The epidemiology of major depressive disorder - Results from the National Comorbidity Survey Replication (NCS-R) [ | 2003 | 274 | 75 | 51 | Harvard University, United States | yes | MD, DrPH |
| 27 | Zarate, CA | 30,380 | A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression [ | 2006 | 131.6 | 633 | 93 | National Institutes of Health, United States | no | MD |
| 28 | Ustun, TB | 30,379 | The World Mental Health (WMH) Survey Initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) [ | 2004 | 152.4 | 105 | 52 | Koc University, Türkiye | no | MD |
| 29 | Miller, AH | 29,560 | Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression [ | 2009 | 162.3 | 361 | 74 | Emory University, United States | yes | MD |
| 30 | Polanczyk, G | 29,347 | Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 [ | 2012 | 471.7 | 173 | 42 | University of São Paulo Medical School, Brazil | no | MD, PhD |
| 31 | Manji, HK | 27,330 | A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression [ | 2006 | 131.6 | 412 | 90 | Oxford University, England | no | MD |
| 32 | Hellhammer, DH | 26,383 | The Trier Social Stress Test- a tool for investigating psychobiological stress responses in a laboratory setting [ | 1993 | 128.4 | 232 | 65 | University of Trier, Germany | no | PhD |
| 33 | Davidson, JR | 26,149 | Development of a new resilience scale: The Connor-Davidson Resilience scale (CD-RISC) [ | 2003 | 216.3 | 340 | 74 | Duke University, United States | yes | MD |
| 34 | Pruessner, JC | 24,124 | Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change [ | 2003 | 124.8 | 360 | 76 | McGill University, Canada | no | PhD |
| 35 | Mintz, J | 23,861 | Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"? [ | 2000 | 93.33 | 345 | 82 | University of California, Los Angeles, United States | yes | PhD |
| 36 | Angold, A | 23,654 | Prevalence and development of psychiatric disorders in childhood and adolescence [ | 2003 | 122.5 | 125 | 71 | Duke University, United States | yes | MD |
| 37 | Keller, MB | 23,378 | The 16-item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression [ | 2003 | 116.3 | 346 | 73 | Brown University, United States | no | MD |
| 38 | Steinhausen, HC | 23,131 | The size and burden of mental disorders and other disorders of the brain in Europe 2010 [ | 2011 | 176.5 | 342 | 73 | University of Southern Denmark, Denmark | no | MD, PhD |
| 39 | Knutson, B | 22,406 | The reward circuit: linking primate anatomy and human imaging [ | 2010 | 162.1 | 154 | 65 | Stanford University, United States | yes | PhD |
| 40 | Walker, EF | 21,623 | Diagnostic and statistical manual of mental disorders [ | 2011 | 5535 | 378 | 55 | Emory University, United States | yes | PhD |
| 41 | Haber, SN | 21,282 | The reward circuit: linking primate anatomy and human imaging [ | 2010 | 162.1 | 211 | 72 | University of Rochester, United States | yes | PhD |
| 42 | Nelson, C | 21,065 | The NimStim set of facial expressions: judgments from untrained research participants [ | 2009 | 160 | 317 | 74 | Harvard University, United States | yes | PhD |
| 43 | Baird, G | 20,939 | Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample [ | 2008 | 127.8 | 171 | 66 | Guy's and St Thomas' NHS Foundation Trust, United States | no | MD |
| 44 | Rohde, LA | 18,699 | The worldwide prevalence of ADHD: a systematic review and metaregression analysis [ | 2007 | 197.6 | 411 | 54 | The Federal University of Rio Grande do Sul, Brazil | no | MD, PhD |
| 45 | Goodman R. | 17,963 | Psychometric properties of the strengths and difficulties questionnaire [ | 2001 | 183.2 | 124 | 58 | Kings College London, England | no | PhD |
| 46 | Simonoff, E | 17,796 | Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample [ | 2008 | 127.8 | 177 | 64 | Kings College London, England | no | MD |
| 47 | Whalen, PJ | 17,684 | The amygdala: vigilance and emotion [ | 2001 | 91.96 | 100 | 48 | University of Wisconsin-Madison, United States | yes | PhD |
| 48 | Etkin, A | 17,321 | Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia [ | 2007 | 129.7 | 127 | 49 | Stanford University, United States | yes | MD, PhD |
| 49 | Monteggia, LM | 16,625 | A neurotrophic model for stress-related mood disorders [ | 2006 | 135.7 | 139 | 49 | Vanderbilt University, United States | yes | PhD |
| 50 | Raison, CL | 16,569 | Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression [ | 2009 | 162.3 | 125 | 47 | University of Wisconsin-Madison, United States | yes | MD |
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Taxonomy
TopicsMental Health Research Topics · Treatment of Major Depression · Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Introduction and background
The new millennium has brought substantial challenges to the field of psychiatry. Data suggest that over 20% of American adults now experience mental illness; the years between 2008 and 2019 saw a 30% increase in mental health diagnoses in adults over 18 [1-4]. However, the increased need for mental healthcare is not reflective of the number of patients receiving the care they need to safely and properly manage their mental health; social stigma, insurance coverage, and lack of access to skilled psychiatric clinicians continue to impede the provision of psychiatric care in this country [5,6]. The balance between demand and supply of mental healthcare in the United States is a problem yet to be resolved, a problem that requires both scaling of existing best practices and research into new and innovative solutions.
While the challenges to psychiatric care in this country are immense, the new millennium has thus far brought great progress to the field. The release of the DSM-5 in 2013 updated psychiatry’s toolbox to treat and diagnose [7]. The discovery and approval of esketamine, the first novel method of action antidepressant in 50 years, has revolutionized options for those suffering from treatment-resistant depression [8]. The development of the Connor-Davidson Resilience Scale (CD-RISC) was able to provide an insightful predictor for patient improvement in response to treatment [9]. Similarly, the assessment and analysis of the CIDI-SF scale, K10/K6 nonspecific distress scales, and the WHO-DAS for the screening of serious mental illnesses have allowed crosstalk between community and clinical epidemiology [10]. The new millennium has brought psychiatry into an unprecedented era of ground-breaking research.
With both the volume of new research in the field and the great progress that has been made in the past two decades, a survey of the most impactful recent advances and top researchers is needed to inform those new to psychiatry. Many bibliometric studies have been dedicated to aggregating and analyzing top-cited articles in psychiatric sub-fields. However, these studies do not provide a broad survey of recent advances in the field [11-14]. To our knowledge, there exists only one other notable psychiatry-wide bibliometric analysis: in 2013, Mazhari sought to identify characteristics of the top 100 most cited articles published in international journals dedicated to psychiatry [15]. Mazhari’s collected articles were published between 1957 and 2005; a study of recent advances in the field and characterization of those innovators making these advances is needed to inform field-wide discussion.
In this study, we use data from the Web of Science (WOS) to analyze all publications in psychiatric journals from January 1, 2000, to September 18, 2022. We characterize both the top 50 most cited articles and the top 50 most impactful authors in psychiatry since 2000 and categorize relevant metrics for each top paper and author. This bibliometric analysis seeks to bridge the current gap in literature by providing a comprehensive analysis of the top authors and articles cited in the entire field of psychiatry in the new millennium, an evaluation that may prove a valuable window into major recent advances and those making these advances in the field.
Review
Methodology
Data Source and Study Sample
This study used data from the Web of Science (WOS) database (Clarivate Analytics PLC), a paid-access platform aggregating scientific and medical journal databases commonly used in bibliometric analyses [16]. The WOS Core Collection platform contains over 85 million records from 1900 present, with data on over 1.8 billion citations [17]. In this study, we included the entire sample of papers published 01/01/2000-10/14/2022 that were published in the journal category “Psychiatry.” While results were tabulated as returned in WOS, cross-verification of all articles was performed in PubMed to verify article authorship. Works that were not original research articles, meeting abstracts, research letters, or editorial materials were excluded from our analysis. Importantly, because WOS defines article categories in part based on journal of publication, psychiatry articles published in general medicine journals were excluded from our analysis.
Measures
Author-specific measures included name, times cited, most cited article, year most cited article was published, average number of times most cited article was cited per year, number of publications, H-index, current or most recently affiliated academic institution as determined through Google search, if the author’s primary institution was one of the top 40 departments of psychiatry receiving National Institutes of Health funding in 2022 as per the Blue Ridge Institute for Medical Research, and highest post-graduate degree(s) [18]. Article-specific measures included times cited, article type (cross-sectional study, clinical classification system, literature review, new measure, new diagnostic tool, randomized controlled trial meta-analysis, statistical method, literature review, or new dataset), title, author names, journal, and year.
Analysis
The top 50 most-cited studies in psychiatric journals were characterized in order of times cited as per WOS records, while the top authors were characterized in order of number of total citations. Median times cited and interquartile ranges (IQR) were calculated for the top articles. The 50 top authors in psychiatry of the new millennium were assessed in this analysis as those authors who were 1) either first or senior (last) authors in one of the top 50 studies previously identified and 2) in the top 50 most-cited psychiatrists within this group. Like top articles, these top authors were also characterized in order of overall times cited per WOS. All analysis was performed in Microsoft Excel.
Study population and characteristics
The WOS database returned a total of 699,005 results for articles published in psychiatric journals from 01/01/2000-09/18/2022. The studies included in this analysis were comprised of 54% original articles (n = 376,569), 29% meeting abstracts (n = 200,475), 5% letters (n = 31,927), 13% editorial materials (n = 49,511), and 6% reviews (n = 40,523). The five countries with the largest number of publications were the United States (35.5%, n = 247,915), followed by England (11.5%, n = 80,243), Germany (8.2%, n = 57,174), Australia (6.6%, n = 45,922), and Canada (6.2%, n = 43,074).
Top articles in psychiatric journals
The 50 highest-cited publications in psychiatric journals since 2000 are listed in Table 1. These publications were cited between 15,001 and 1,964 times. “Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication” was the highest-cited publication with 15,001 citations. In this landmark 2005 cross-sectional analysis, Kessler et al. shed light on the prevalences of DSM-IV psychiatric disorders in adults, work that has proven foundational not only to the field of psychiatric epidemiology but to psychiatry as a whole. A commentary letter entitled “Diagnostic and Statistical Manual of Mental Disorders” was reported as the second highest cited publication with 8,592 citations in the WOS database; cross-validation of this article using the article’s PubMed ID (21741095) revealed only 24 citations. Upon further inquiry, it became clear this article had erroneously received credit for citations in WOS that should have been attributed to the DSM-V. Finally, “Short screening scales to monitor population prevalences and trends in non-specific psychological distress” was reported as the third highest-cited article with 5,559 citations in WOS. In this article describing new clinical measures, Kessler et al. discuss the implementation and validation of two screening scales for psychological distress, the K6 and K10.
Cross-sectional, new measure, literature review, and RCT publications were the most popular article types among the 50 highest-cited publications. For cross-sectional publications, the median number of citations was 2,396 (interquartile range (IQR): 2,129-3,183). For new-measure publications, the median number of citations was 2,559 (IQR: 2,450-3,573). For literature review publications, the median number of citations was 2,559 (IQR: 2,380-3,175). For RCT publications, the median number of citations was 2,548 (IQR: 2,269-3,057). The overall median across all publication types was 2,457 (IQR: 2,198-3,165). The three most popular journals within these top-cited publications included the American Journal of Psychiatry (eight publications), Biological Psychiatry (seven publications), and JAMA Psychiatry (formerly named Archives of General Psychiatry) (seven publications).
Top authors in psychiatry
The 50 most cited authors in psychiatry are listed in Table 2. The top five authors collectively had 445,740 citations and 3,635 publications. Of the 50 most-cited publications, female authors comprised 12 of the 50 (24%) first authors and 10 of the 50 (20%) senior authors. Of the 50 most cited authors in psychiatry, 11 (22%) were female authors. Notably, Ronald Kessler was the author of seven of the 50 publications. Of the 50 most cited authors in psychiatry, 27 (54%) authors were associated with a top 40 NIH-funded psychiatry program in the US. The top three university affiliations of top authors included Harvard University (five authors), Duke University (four authors), and Columbia University (three authors). All but one top author had a PhD/DrPH (23), MD (21), or both of these degrees (5).
Discussion of findings
This study used the Web of Science (WOS) database of articles published in psychiatric journals from 01/01/2000-09/18/2022 to identify the 50 most cited publications as well as the 50 most cited authors for a bibliometric analysis. Within the 50 most cited psychiatric journal publications of the new millennium, the analysis found that, first, these publications were cited between 1,964 and 15,001 times. Second, the most popular types of highly cited articles were cross-sectional studies, new measures, literature reviews, and randomized controlled trials. Third, the journal with the most top 50 highest-cited publications was the American Journal of Psychiatry, with eight out of the top 50 publications.
Our authorship analysis revealed, first, that female authors remain underrepresented in recent advances in psychiatry, comprising 12 of the 50 first authors of top psychiatry articles and 10 of the 50 senior authors of top psychiatry articles. Within the 50 top authors, just 11 (22%) were female authors. This percentage is similar to the 23% of psychiatry department chairs who were female in a recent analysis of women in academic psychiatry, despite women accounting for 34% of full professors in the field [85]. Second, our analysis showed that 27 (54%) top-50 authors were affiliated with a top 40 NIH-funded psychiatry program in the US, with an additional six (12%) authors affiliated with the NIH itself. Thus, approximately two-thirds of top authors in psychiatry across the world work within the NIH or one of the top 40 US psychiatry departments to which it grants funding. A third of top authors in psychiatry were affiliated with just four US institutions: 36% of top authors were affiliated with the NIH, Harvard University, Duke University, or Columbia University. Third, this analysis shows that MDs and PhDs appear to contribute to top-cited articles in psychiatry relatively equally; from this analysis, it appears that holding an MD or a PhD is nearly universal among top authors in the field, but those with either degree can reach the top levels of impact in the field.
Many bibliometric studies have concentrated on specific subfields of psychiatry rather than the general field; one salient exception was a bibliometric analysis conducted by Mazhari in 2013 [15]. There is a paucity of studies that provide a broad survey of the recent psychiatric advances of the past two decades. Mazhari’s study focused on the top 100 publications and considered publications between 1957 and 2005 [15]. This study includes the characteristics of the most-cited researchers across psychiatry in addition to the top publications, an additional dimension that adds to prior field-wide knowledge of top articles. Our criteria for inclusion as a “top author” presents a more nuanced look at leading authorship compared to measures such as H-index and provides a less ephemeral look at productive contributions to the field than resources such as the Blue Ridge Institute’s yearly characterization of top grant-getters in psychiatry [18]. Thus, this study attempts to fill the gap in current literature by highlighting recent advances and those at the forefront of psychiatry in a manner that captures recent and lasting literary impact. Furthermore, it examines an uncharacterized recent period in the field, starting in 2000.
This study had several notable limitations. First, when the publications found in the WOS database were cross-verified with PubMed, this revealed that the article “Diagnostic and Statistical Manual of Mental Disorders” was erroneously reported to be cited more than it actually had been in the WOS database. Other limitations of this data source and our search criteria are the limited inclusion of relevant articles in psychiatry published in journals nonspecific to psychiatry, including the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial and genome-wide association studies showing relevance for bipolar I disorder [86,87]. Other notable exclusions include articles published by NEJM, JAMA, and JAMA Internal Medicine pertaining to opioid- and cannabis-related areas of study of interest to both psychiatrists and general medicine. Finally, this study did not investigate the temporal aspect of the top publications or authors; thus, some publications could potentially be cited more frequently simply due to their earlier date of publication than because of their relative contribution to psychiatry.
Conclusions
This study is one of the few to report top authors and articles in psychiatry for those interested in a broad overview of the field. More specifically, we highlight the characteristics of the most-cited publications and authors in psychiatry, which shows both types of articles and the authors who end up receiving the largest number of citations. Understanding these recent top authors and their highly cited articles can serve as a useful starting point for anyone wishing to obtain a broad education in the recent history of psychiatry, as well as those one day hoping to become top authors in the field themselves.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
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