# Surgical resection of brain and adrenal gland metastases from gastric cancer: a case report and literature review

**Authors:** Yuto Kitano, Shigekazu Ohyama, Yasumichi Yagi, Ichiro Onishi, Masato Kayahara

PMC · DOI: 10.1093/jscr/rjae163 · 2024-03-21

## TL;DR

A patient with gastric cancer underwent surgery for brain and adrenal metastases, but ultimately died from cancer-related complications.

## Contribution

A rare case report of surgical resection of brain and adrenal metastases from gastric cancer with literature review.

## Key findings

- The patient underwent successful resection of cerebellar and adrenal metastases from gastric cancer.
- Despite surgery and treatment, the patient died of meningitis carcinomatosa one year later.
- Few reports document long-term survival after brain metastasis resection in gastric cancer.

## Abstract

The prognosis of recurrent gastric cancer is generally poor, and aggressive surgical treatment is rarely performed. Herein, we present the case of a patient who underwent resection of cerebellar and adrenal gland metastases from gastric cancer. The patient was treated for gastric cancer with distal gastrectomy at 23 years and for remnant gastric cancer with completion gastrectomy at 48 years. At 59 years old, she experienced vertigo and nausea and was diagnosed with cerebellar and left adrenal gland tumours. First, the cerebellar tumours were resected and diagnosed as metastases of gastric cancer. After 1 month, the adrenal gland tumour was resected and diagnosed as metastatic. She underwent whole-brain radiotherapy and subsequent chemotherapy with S-1. One year after the surgery, the patient died of meningitis carcinomatosa. There are few reports on long-term survival after the resection of brain metastases. Herein, we report our experience along with a review of the literature.

## Linked entities

- **Chemicals:** S-1 (PubChem CID 1497102)
- **Diseases:** gastric cancer (MONDO:0001056)

## Full-text entities

- **Diseases:** adrenal gland (MESH:D000307), gastric cancer (MESH:D013274), vertigo (MESH:D014717), meningitis carcinomatosa (MESH:D008580), nausea (MESH:D009325), metastases (MESH:D009362), cerebellar tumours (MESH:D002528), adrenal gland tumour (MESH:D000310)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10958142/full.md

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Source: https://tomesphere.com/paper/PMC10958142