# Metastatic mucinous adenocarcinoma from breast mimicking a pyogenic granuloma in the gingiva: a case report

**Authors:** Rudra Prasad Chatterjee, Sangeeta Sinha, Debdita Banerjee, Lamia Parveen, Sanchita Kundu

PMC · DOI: 10.11604/pamj.2024.47.14.36983 · The Pan African Medical Journal · 2024-01-11

## TL;DR

A rare case of breast cancer spreading to the gums was mistaken for a benign growth, highlighting the need for careful diagnosis.

## Contribution

This case report adds to the limited literature on metastatic mucinous adenocarcinoma in the oral region and emphasizes diagnostic challenges.

## Key findings

- Metastatic mucinous adenocarcinoma from the breast was diagnosed in a 51-year-old woman with gingival swelling.
- The lesion mimicked a benign pyogenic granuloma, emphasizing the importance of histological and immunohistochemical evaluation.
- Such tumors are rare, accounting for about 1% of oral malignant neoplasms with a predilection for the gingiva.

## Abstract

Mucin-producing adenocarcinomas (MAC) are an extremely rare, indistinct group of neoplasm having either a salivary gland origin or with prominent glandular component. The diagnosis is chiefly based on the histological aspect conjoined with immunohistochemical evaluation as clinico-radiographical features are non-specific. It can arise as a primary metastasis to soft tissues, most commonly from either lung, breast, kidney, or colon. This paper reports a 51-year-old woman with buccolingual gingival swelling having a final diagnosis of metastatic mucinous adenocarcinoma from the breast. A tissue biopsy was performed followed by immunohistochemistry that confirmed the diagnosis. They are extremely rare, making the diagnosis challenging as it may mimic a benign neoplasm. It accounts for approximately 1% of all oral malignant neoplasms having gingival propensity. The clinician should therefore take into account every diagnostic aspect while encountering such oral lesions to achieve proper patient welfare.

## Linked entities

- **Diseases:** mucinous adenocarcinoma (MONDO:0004957), pyogenic granuloma (MONDO:0022096), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** benign neoplasm (MESH:D009369), pyogenic granuloma (MESH:D017789), breast (MESH:D061325), gingival swelling (MESH:D005891), oral lesions (MESH:D009059), MAC (MESH:D002288)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10957724/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC10957724/full.md

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Source: https://tomesphere.com/paper/PMC10957724