# High-grade serous papillary ovarian carcinoma combined with nonkeratinizing squamous cell carcinoma of the cervix: a case report

## TL;DR

A rare case of two gynecologic cancers in one patient is reported, with successful treatment and remission achieved.

## Contribution

This case report highlights the coexistence of two rare primary malignancies in the ovary and cervix.

## Key findings

- The patient achieved complete remission after six cycles of Taxol and Carboplatin chemotherapy.
- BRCA2 mutation testing and PARP inhibitors were used for maintenance therapy.

## Abstract

Multiple primary malignant neoplasms are a rare gynecologic malignancy; particularly, cases originating from the heterologous organs, such as the ovary and cervix. Here, we report a case of two primary malignant neoplasms in a patient who had undergone laparoscopic radical hysterectomy + bilateral salpingo-oophorectomy + pelvic lymph node dissection + para-aortic lymphadenectomy + appendectomy + omentectomy + metastasectomy under general anesthesia. The patient experienced complete remission after six courses of postoperative chemotherapy with a standard Taxol and Carboplatin regimen. Genetic testing was performed to detect BRCA2 mutations, and poly (ADP-ribose) polymerase (PARP) inhibitors were used for maintenance therapy.