# Extended-Spectrum Beta-Lactamase Escherichia coli-Associated Acute Cholangitis: Uncommon Patient Characteristics and Clinical Implications

**Authors:** Somin Lee, Abeer Qasim, Ahmed Alemam, Misbahuddin Khaja, Anil Dev

PMC · DOI: 10.7759/cureus.54533 · Cureus · 2024-02-20

## TL;DR

This case report discusses an unusual case of acute cholangitis in an elderly patient caused by antibiotic-resistant Escherichia coli.

## Contribution

The report emphasizes the importance of recognizing diverse clinical presentations in elderly patients with antibiotic-resistant infections.

## Key findings

- An elderly patient presented with acute cholangitis caused by extended-spectrum beta-lactamase-producing Escherichia coli.
- The case highlights the need for understanding patient risk factors to guide appropriate antibiotic selection.

## Abstract

Acute cholangitis is a potentially life-threatening condition caused by an infection of the biliary tract resulting from biliary obstruction. This case report highlights an unusual presentation of acute cholangitis in an elderly patient characterized by the presence of extended-spectrum beta-lactamase-producing Escherichia coli. We aim to emphasize the significance of recognizing diverse clinical manifestations in the elderly population to enhance timely diagnosis and appropriate management. The case highlights the importance of better understanding patient risk factors for potential causative organisms and their susceptibility to selecting proper antibiotics and improving clinical outcomes.

## Linked entities

- **Diseases:** acute cholangitis (MONDO:0001930)
- **Species:** Escherichia coli (taxon 562)

## Full-text entities

- **Diseases:** Acute Cholangitis (MESH:D000208), biliary obstruction (MESH:D001658), infection of the biliary tract (MESH:D001660)
- **Species:** Escherichia coli (E. coli, species) [taxon 562], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC10956482/full.md

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Source: https://tomesphere.com/paper/PMC10956482