# Prenatal Diagnosis of Hemimegalencephaly Using Radiological Methods: A Case Report

**Authors:** Marcia Mejia, Santiago Vargas Arango, Sergio Vargas Vélez, Jonathan Pimiento Figueroa

PMC · DOI: 10.7759/cureus.54456 · Cureus · 2024-02-19

## TL;DR

This case report describes the prenatal diagnosis of hemimegalencephaly, a rare brain condition, using radiological methods like fetal MRI.

## Contribution

The paper highlights the use of fetal MRI for confirming prenatal hemimegalencephaly diagnosis.

## Key findings

- Hemimegalencephaly was diagnosed in a 23-week-old fetus using prenatal imaging.
- Fetal MRI was crucial in confirming the diagnosis and assessing brain abnormalities.
- Early prenatal detection can help in planning appropriate postnatal care.

## Abstract

Hemimegalencephaly is a rare congenital anomaly characterized by an increase in the size and dysplastic involvement of one cerebral hemisphere, which can be partial or complete. It may also be associated with anomalies in the cerebellum and brainstem and, in some cases, be a part of different syndromes. The result of these abnormalities leads to intractable epilepsy and developmental delay. Diagnosis is typically made through imaging studies in the postnatal period, but it can also be done before birth. We present the case of a 23-week pregnant patient in whom a prenatal diagnosis of hemimegalencephaly was made, highlighting the need for fetal magnetic resonance imaging (MRI) to confirm the diagnosis.

## Linked entities

- **Diseases:** hemimegalencephaly (MONDO:0020492), epilepsy (MONDO:0005027)

## Full-text entities

- **Diseases:** epilepsy (MESH:D004827), developmental delay (MESH:D002658), Hemimegalencephaly (MESH:D065705), anomalies in the cerebellum and brainstem (MESH:D002526), congenital anomaly (MESH:D000013)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10951679/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC10951679/full.md

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Source: https://tomesphere.com/paper/PMC10951679