# An Unusual Presentation of Villoglandular Papillary Adenocarcinoma in a Perimenopausal Woman

**Authors:** Priya R Nair, Saunitra A Inamdar, Minal A Kalambe, Aakanksha Dewangan

PMC · DOI: 10.7759/cureus.54374 · Cureus · 2024-02-17

## TL;DR

A 46-year-old perimenopausal woman was diagnosed with a rare cervical cancer called villoglandular papillary adenocarcinoma and treated with surgery and radiation.

## Contribution

This case report highlights the unusual presentation of VPA in a perimenopausal woman.

## Key findings

- VPA was diagnosed in a 46-year-old woman with a vaginal mass and irregular menses.
- The patient underwent radical hysterectomy and post-operative radiation therapy.
- VPA is typically seen in reproductive-age individuals but can occur in perimenopausal women.

## Abstract

Villoglandular papillary adenocarcinoma (VPA) or villoglandular adenocarcinoma (VGA) is a rare but well-recognized subtype of cervical carcinoma. It exhibits a favorable prognosis, particularly within the childbearing age group, and is considered a rare manifestation of mucinous adenocarcinoma typically observed in individuals of reproductive age. In comparison to other adenocarcinomas, VPA generally demonstrates a more optimistic prognosis. This report details the case of a 46-year-old perimenopausal woman who presented with complaints of irregular menses and a protruding mass from the vagina. Upon examination, an exophytic growth was identified, replacing the cervix. A biopsy confirmed the diagnosis of VPA. Subsequently, the patient underwent a radical hysterectomy, followed by post-operative radiation therapy.

## Linked entities

- **Diseases:** cervical carcinoma (MONDO:0005131), mucinous adenocarcinoma (MONDO:0004957)

## Full-text entities

- **Diseases:** cervical carcinoma (MESH:D002583), VPA (MESH:D000231), mucinous adenocarcinoma (MESH:D002288), VGA (MESH:D000230), menses (MESH:D008599)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC10948958/full.md

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Source: https://tomesphere.com/paper/PMC10948958